catalog number :
MBS203131
products type :
Recombinant Protein
products full name :
Mouse IL1 beta, 118-269aa, Mouse, His tag, Recombinant, E Coli
products short name :
IL1 beta
products name syn :
IL-1b; IL-1beta; Interleukin 1 beta; Mouse IL1 beta; Interleukin 1 beta Catabolin; H1; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL1B; IL1F2; Interleukin 1 beta precursor; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta.
other names :
interleukin-1 beta; Interleukin-1 beta; interleukin-1 beta; IL-1 beta; interleukin 1 beta
products gene name :
IL1 beta
other gene names :
Il1b; Il1b; Il-1b; IL-1beta; IL-1 beta
uniprot entry name :
IL1B_MOUSE
sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS
purity :
> 90% by SDS - PAGE
form :
Liquid in 20mM Tris pH 8.0, 10% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Mouse. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Hormones & Cytokines
products description :
IL-1beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1beta is required for tumor growth, metastasis, and angiogenesis in several animal models. Recombinant mouse IL-1beta, fused to His tag, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Saijo Y, et al, (2002) J. Immunol. 169:469-475. Torisu H, et al, (2000) J. Cancer. 85:182-188.
ncbi gb acc num :
NM_008361.3
ncbi mol weight :
21kDa (189aa), confirmed by MALDI-TOF.
ncbi pathways :
African Trypanosomiasis Pathway 194387!!African Trypanosomiasis Pathway 194323!!Alzheimer's Disease Pathway 83294!!Alzheimer's Disease Pathway 509!!Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Chagas Disease (American Trypanosomiasis) Pathway 147810!!Chagas Disease (American Trypanosomiasis) Pathway 147795