protein

Recombinant Early Endosome Antigen 1 (EEA1)

MBS2031249

0.01 mg

140 USD

Recombinant Protein

Recombinant Early Endosome Antigen 1 (EEA1)

[Early Endosome Antigen 1]

[early endosome antigen 1; Early endosome antigen 1; early endosome antigen 1; early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2]

[EEA1]

[EEA1; EEA1; MST105; ZFYVE2; MSTP105; ZFYVE2]

EEA1_HUMAN

E Coli

>97%

100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.

Original Concentration: 200 ug/mL

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

Positive Control; Immunogen, SDS-PAGE, Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.)

SDS-Page

Testing Data (TD)

Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: His1232~Lys1348. Tags: N-terminal His Tag . Subcellular Location: Membrane, Cytoplasm. Traits: Freeze-dried powder. Predicted isoelectric point: 7.2. Predicted Molecular Mass: 17.0kDa. Accurate Molecular Mass: 17kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

55770888

NP_003557.2

NM_003566.3

Endocytosis Pathway (102279); Endocytosis Pathway (102181); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Phagosome Pathway (153910); Phagosome Pathway (153859); Toll Like Receptor 9 (TLR9) Cascade Pathway (1269233); Toll-Like Receptors Cascades Pathway (1269204); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

EEA1: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Interacts with ERBB2. Protein type: C2H2-type zinc finger protein; Vesicle. Chromosomal Location of Human Ortholog: 12q22. Cellular Component: extrinsic to plasma membrane; recycling endosome; membrane; early endosome membrane; cytoplasm; early endosome; cytoplasmic vesicle; cytosol; serine-pyruvate aminotransferase, type 2B complex. Molecular Function: calmodulin binding; protein binding; protein homodimerization activity; zinc ion binding; GTP-dependent protein binding; phosphatidylinositol binding. Biological Process: vesicle fusion; early endosome to late endosome transport; endocytosis; synaptic vesicle to endosome fusion

0.01 mg

140 USD

0.05 mg

255

0.1 mg

390

0.2 mg

480

0.5 mg

935

1 mg

1380