catalog number :
MBS203121
products type :
Recombinant Protein
products full name :
GM-CSF, 18-141aa, Mouse, Recombinant, E Coli
products short name :
GM-CSF
products name syn :
Csf2; Csfgm; MGI-IGM; mGM-CSF; Granulocyte-macrophage colony stimulating factor 2; Granulocyte-macrophage colony stimulating factor 2
other names :
granulocyte-macrophage colony-stimulating factor; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; granulocyte-macrophage colony stimulating factor 2; put. GM-CSF; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF
products gene name :
GM-CSF
other gene names :
Csf2; Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM; Csfgm; GM-CSF; CSF
uniprot entry name :
CSF2_MOUSE
sequence :
MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
purity :
> 95% by SDS - PAGE
form :
Liquid in phosphate-buffered saline (PBS), pH 7.4, 10% glycerol
concentration :
1 mg/ml (determined by BCA assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Mouse
other info2 :
Expression System: E Coli
products categories :
Hormones & Cytokines
products description :
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Mouse GM-CSF protein is 125 amino acids and shares approximately 60% homology with the human GM-CSF protein. Recombinant mouse GM-CSF was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
products references :
Fleetwood AJ., et al, (2005). Crit Rev Immunol. 25(5):405-28. Hamilton JA., et al. (2004). Growth Factors. 22(4):225-31.
ncbi gb acc num :
NM_009969.4
ncbi mol weight :
14 kDa (125 aa), confirmed by MALDI-TOF.
ncbi pathways :
Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Cytokine Signaling In Immune System Pathway 1110778!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198283!!Fc Epsilon RI Signaling Pathway 83279!!Fc Epsilon RI Signaling Pathway 493!!G Beta:gamma Signalling Through PI3Kgamma Pathway 1110535!!G-protein Beta:gamma Signalling Pathway 1110534