product summary
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company name :
MyBioSource
product type :
protein
product name :
HSP10, 1-102aa, Human, Recombinant, E Coli
catalog :
MBS203119
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203119
products type :
Recombinant Protein
products full name :
HSP10, 1-102aa, Human, Recombinant, E Coli
products short name :
HSP10
products name syn :
Chaperonin 10; CPN10; GroES; Heat shock protein 10; HSP10; Heat shock protein 10 10 kDa chaperonin; HSPE 1; HSPE1; 10 kDa heat shock protein mitochondrial; Cpn 10; Early pregnancy factor; EPF; Heat shock 10kD protein 1; Heat shock 10kD protein 1 chaperonin 10; Heat shock 10kDa protein 1; HSP 10; HSP10; Heat shock 10kDa protein 1 chaperonin 10
other names :
10 kDa heat shock protein, mitochondrial; 10 kDa heat shock protein, mitochondrial; 10 kDa heat shock protein, mitochondrial; 10 kDa chaperonin; chaperonin 10; early-pregnancy factor; heat shock 10kD protein 1 (chaperonin 10); heat shock 10kDa protein 1; 10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
products gene name :
HSP10
other gene names :
HSPE1; HSPE1; EPF; CPN10; GROES; HSP10; Hsp10; CPN10; EPF
uniprot entry name :
CH10_HUMAN
sequence length :
102
sequence :
MAGQAFRKFL PLFDRVLVER SAAETVTKGG IMLPEKSQGK VLQATVVAVG SGSKGKGGEI QPVSVKVGDK VLLPEYGGTK VVLDDKDYFL FRDGDILGKY VD
purity :
> 95% by SDS - PAGE
form :
Liquid in 20mM Tris pH 8.0, 50mM NaCl
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
products categories :
Heat Shock Proteins
products description :
Heat shock protein (HSP) 10 is a member of the highly conserved group of molecular chaperons, which are necessary for efficient folding of many proteins in normal and stress conditions and have been implicated in several human diseases. HSP10 is the ~10kD mammalian equivalent to GroES of E.coli. The function of Hsp10 is to bind Hsp60 (also known as chaperonin-60), in the presence of ATP, thereby promoting a conformational change in Hsp60 and enclosing the protein substrate within the complex. ATP hydrolysis by Hsp60 destabilizes the Hsp60/ Hsp10 complex, allowing it to dissociate and release the substrate protein. Recombinant human HSP10 was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Lin KM., et al. (2004), FASEB J. 18(9):1004-6. Hohfeld J., et al. (1994), J. Cell BIol. 126(2):305-15
ncbi gi num :
4504523
ncbi acc num :
NP_002148
ncbi gb acc num :
NM_002157.2
ncbi mol weight :
10 kDa (102 aa), confirmed by MALDI-TOF.
ncbi summary :
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
uniprot summary :
HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family. Protein type: Mitochondrial. Chromosomal Location of Human Ortholog: 2q33.1. Cellular Component: membrane; mitochondrion; mitochondrial matrix. Molecular Function: protein binding; chaperone binding; unfolded protein binding; ATP binding. Biological Process: osteoblast differentiation; caspase activation; protein folding; response to unfolded protein
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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