protein

FABP1, 1-127aa, Human, His-tag, Recombinant, E Coli

MBS203114

0.1 mg

310 USD

Recombinant Protein

FABP1, 1-127aa, Human, His-tag, Recombinant, E Coli

FABP1

Fatty acid-binding protein; liver; FABPL; L-FABP; FABP1; Fatty acid binding protein 1; fatty acid binding protein 1 liver

fatty acid-binding protein, liver; Fatty acid-binding protein, liver; fatty acid-binding protein, liver; fatty acid-binding protein 1; liver-type fatty acid-binding protein; fatty acid binding protein 1, liver; Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP

FABP1

FABP1; FABP1; FABPL; L-FABP; FABPL; L-FABP

FABPL_HUMAN

127

MGSSHHHHHH SSGLVPRGSH MSFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS VTELNGDIIT NTMTLGDIVF KRISKRI

> 95% by SDS - PAGE

Liquid in 20mM Tris pH 8.0

1 mg/ml (determined by Bradford assay)

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

SDS-PAGE

Antigen Species: Human. Tag: His-tag

Expression System: E Coli. Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)

Cancer

FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallel beta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm; it may be involved in intracellular lipid transport and metabolism. Recombinant human FABP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Atshaves BP., et al. (2004). Mol Cell Biochem. 259(1-2): 115-29. Nakamura T., et al.(2005). Diabestes Care. 28(11) : 2728-32.

4557577

NP_001434

NM_001443.2

16kDa (147aa), confirmed by MALDI-TOF.

Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); Selenium Metabolism And Selenoproteins Pathway (198846)

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 2p11. Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol. Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; drug binding; long-chain fatty acid transporter activity; chromatin binding; fatty acid binding. Biological Process: long-chain fatty acid transport; positive regulation of hydrolase activity; positive regulation of cell proliferation; cellular lipid metabolic process; negative regulation of caspase activity; negative regulation of apoptosis; positive regulation of fatty acid beta-oxidation; intestinal absorption

0.1 mg

310 USD

0.5 mg

720