catalog number :
MBS2031084
products type :
Recombinant Protein
products full name :
Recombinant Secretogranin III (SCG3)
products short name :
[Secretogranin III]
other names :
[secretogranin III; Secretogranin-3; secretogranin-3; secretogranin III; Secretogranin III; SgIII]
products gene name :
[SCG3]
other gene names :
[SCG3; SCG3; SGIII; SgIII]
uniprot entry name :
SCG3_HUMAN
form :
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% sarcosyl, 5%Trehalose.
concentration :
Original concentration: 1000 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
SDS-Page
image2 heading :
Testing Data (TD)
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Traits: Freeze-dried powder. Residues: Phe20~Leu468. Tags: N-terminal His Tag . Subcellular Location: Cytoplasm
other info2 :
Predicted isoelectric point: 4.9. Predicted Molecular Mass: 63.7kDa. Accurate Molecular Mass: 64kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
AAD44483.1
ncbi pathways :
Hemostasis Pathway (1269340); Platelet Activation, Signaling And Aggregation Pathway (1269350); Platelet Degranulation Pathway (1269367); Response To Elevated Platelet Cytosolic Ca2+ Pathway (1269365)
ncbi summary :
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
uniprot summary :
SCG3: 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 15q21. Cellular Component: extracellular region. Biological Process: platelet activation; platelet degranulation; blood coagulation