protein

Recombinant Inter Alpha-Globulin Inhibitor H3 (ITIH3)

MBS2031080

0.01 mg

145 USD

Recombinant Protein

Recombinant Inter Alpha-Globulin Inhibitor H3 (ITIH3)

[Inter Alpha-Globulin Inhibitor H3]

[inter-alpha-trypsin inhibitor heavy chain H3 preproprotein; Inter-alpha-trypsin inhibitor heavy chain H3; inter-alpha-trypsin inhibitor heavy chain H3; inter-alpha-trypsin inhibitor heavy chain 3; Serum-derived hyaluronan-associated protein; SHAP]

[ITIH3]

[ITIH3; ITIH3; H3P; SHAP; ITI-HC3; ITI heavy chain H3; ITI-HC3; Inter-alpha-inhibitor heavy chain 3; SHAP]

ITIH3_HUMAN

Host: E Coli

Homo sapiens (Human)

890

> 95%

Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.

Original Concentration : 200 Ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)

SDS-Page

. Source: Prokaryotic expression. Residues: Pro279~Val467. Tags: N-terminal His Tag. Subcellular Location: Secreted. Traits: Freeze-dried powder. Buffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

. Predicted isoelectric point: 5.5. Predicted Molecular Mass: 25.2kDa. Accurate Molecular Mass: 26kDa as determined by SDS-PAGE reducing conditions. [ USAGE ]: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

133925809

NP_002208.3

NM_002217.3

This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. Polymorphisms of this gene may be associated with increased risk for schizophrenia and major depressive disorder. This gene is present in an inter-alpha-trypsin inhibitor family gene cluster on chromosome 3. [provided by RefSeq, Jul 2015]

ITIH3: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Belongs to the ITIH family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Inhibitor. Chromosomal Location of Human Ortholog: 3p21.1. Cellular Component: extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity. Biological Process: hyaluronan metabolic process

0.01 mg

145 USD

0.05 mg

280

0.1 mg

440

0.2 mg

540

0.5 mg

1040

1 mg

1545