product summary
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company name :
MyBioSource
product type :
protein
product name :
Thioredoxin-1 Human, Recombinant, E Coli
catalog :
MBS203108
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203108
products type :
Recombinant Protein
products full name :
Thioredoxin-1 Human, Recombinant, E Coli
products short name :
Thioredoxin-1
products name syn :
TRX1; TRX2; Thioredoxin-1; Thioredoxin I; TR-I; Thioredoxin-2; Thioredoxin-1; ADF; Surface associated sulphydryl protein; TXN protein; ATL derived factor; DKFZp686B1993; MGC61975; SASP; Thioredoxin; TRDX; TRX; TRX 1; TXN
other names :
thioredoxin isoform 1; Thioredoxin; thioredoxin; ADF; ATL-derived factor; SASP; TXN delta 3; surface-associated sulphydryl protein; thioredoxin delta 3; thioredoxin; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP
other gene names :
TXN; TXN; TRX; TRDX; TRX1; TRDX; TRX; TRX1; Trx; ADF; SASP
uniprot entry name :
THIO_HUMAN
sequence length :
105
sequence :
MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV
purity :
> 95% by SDS - PAGE
form :
Liquid. In Phosphate buffer saline(PBS), pH 7.4
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli. Bioactivity: Specific activity is 7-10 A650/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin. Please refer to our activity assay protocol. Assay: 1. Prepare a 1ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris, 63mM sodium phosphate, 1mM DTT, 0.1% (w/v) insulin, 2mM EDTA. 2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately. 3. Incubate at 25C for 20 minutes. 4. Record the increase in A650nm for 15 minutes
products categories :
Redox Proteins
products description :
Thioredoxin(Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. Recombinant human thioredoxin-1 was overexpressed in E. coli and purified by using conventional chromatography techniques
products references :
Pigiet VP., et al.(1986) Proc. Natl.Acad.Sci. uSA 83(20):7643-7. Lundstrom J., et al. (1990) J.Biol.Chem. 265(16):9114-20. Laurent TC., et al. (1964) J Biol Chem. 239:3436-44.
ncbi gi num :
50592994
ncbi acc num :
NP_003320
ncbi gb acc num :
NM_003329.3
ncbi mol weight :
11.7 kDa (105 aa), confirmed by MALDI-TOF.
ncbi pathways :
Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Folic Acid Network Pathway 920880!!Folic Acid Network Pathway 219799!!Folic Acid Network Pathway 198383!!Immune System Pathway 106386!!Inflammasomes Pathway 366166!!Innate Immune System Pathway 106387!!Metabolism Pathway 477135
ncbi summary :
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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