product summary
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company name :
MyBioSource
product type :
protein
product name :
AGR 2, 21-175aa, Human, His-tag, Recombinant, E Coli
catalog :
MBS203107
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203107
products type :
Recombinant Protein
products full name :
AGR 2, 21-175aa, Human, His-tag, Recombinant, E Coli
products short name :
AGR 2
products name syn :
AG2; GOB-4; HAG-2; XAG-2; Anterior gradient 2 homolog; AGR 2; Anterior gradient 2 homolog; AGR2; anterior gradient homolog 2 (Xenopus laevis); PDIA17; protein disulfide isomerase family A member 17; Anterior Gradient Protein 2 Homolog
other names :
anterior gradient protein 2 homolog; Anterior gradient protein 2 homolog; anterior gradient protein 2 homolog; AG-2; HPC8; anterior gradient homolog 2; epididymis secretory protein Li 116; protein disulfide isomerase family A, member 17; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; anterior gradient 2; HPC8; Secreted cement gland protein XAG-2 homolog
products gene name :
AGR 2
other gene names :
AGR2; AGR2; AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116; AG2; AG-2; hAG-2
uniprot entry name :
AGR2_HUMAN
sequence length :
175
sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMRDT TVKPGAKKDT KDSRPKLPQT LSRGWGDQLI WTQTYEEALY KSKTSNKPLM IIHHLDECPH SQALKKVFAE NKEIQKLAEQ FVLLNLVYET TDKHLSPDGQ YVPRIMFVDP SLTVRADITG RYSNRLYAYE PADTALLLDN MKKALKLLKT EL
purity :
> 95% by SDS - PAGE
form :
Liquid in 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol, 1mM EDTA
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cancer
products description :
AGR2(Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein(XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Recombinant human AGR2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
F.R. Fritzsche. et al., (2007). Histol Histopathol. 22: 703-708. Fletcher GC. et al., (2003) Br J Cancer 88(4): 579-85 . Liu D. et al., (2005) Cancer Res. 65 : 3796-805.
ncbi gi num :
5453541
ncbi acc num :
NP_006399
ncbi gb acc num :
NM_006408.3
ncbi mol weight :
22 kDa (192 aa), confirmed by MALDI-TOF.
uniprot summary :
AGR2: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Interacts with LYPD3 and DAG1 (alphaDAG1). Interacts with MUC2; disulfide-linked. Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. Belongs to the AGR family. Protein type: Oncoprotein; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7p21.3. Cellular Component: mitochondrion; endoplasmic reticulum; extracellular region. Molecular Function: protein binding
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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