product summary
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company name :
MyBioSource
product type :
protein
product name :
Recoverin, 1-200 aa, Human, E Coli
catalog :
MBS203104
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS203104 image 1
product information
catalog number :
MBS203104
products type :
Recombinant Protein
products full name :
Recoverin, 1-200 aa, Human, E Coli
products short name :
[Recoverin]
products name syn :
[RCVRN; RCV1; Recoverin; Cancer-associated retinopathy protein; Protein CAR; Recoverin; Cancer associated retinopathy protein; Cancer associated retinopathy protein antibody; CAR protein,]
other names :
[recoverin; Recoverin; recoverin; recoverin; Cancer-associated retinopathy protein; Protein CAR]
other gene names :
[RCVRN; RCVRN; RCV1; RCV1; Protein CAR]
host :
E Coli
sequence length :
200
sequence :
MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDT DPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKN EVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK EILRLIQFEP QKVKEKMKNA
purity :
> 95% by SDS-PAGE
form :
Liquid. In 20 mM Tris pH 8.0, 1 mM EDTA, 2mM MgCl2, 10% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human
products categories :
Cancer
products description :
Recoverin is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft in the protein drives the translocation of recoverin from solution to the disc membrane. Recently, recoverin is a detectable serologic protein that is expressed in patients with cancer-associated retinopathy, a paraneoplastic syndrome. Recombinant human recoverin was overexpressed in E. coli and purified by using conventional chromatography techniques
products references :
Sampath P., et al. (2004) Cancer Control. 11, 174-80. Erickson MA., et al. (1998) Proc. Natl. Acad. Sci. 95, 6474-9.
ncbi gi num :
4506459
ncbi acc num :
NP_002894
ncbi gb acc num :
NM_002903.2
uniprot acc num :
P35243
ncbi mol weight :
23 kDa (200 aa), confirmed by MALDI-TOF.
ncbi pathways :
Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway (1269629); Phototransduction Pathway (149806); Phototransduction Pathway (148660); Signal Transduction Pathway (1269379); The Phototransduction Cascade Pathway (1269627); Visual Phototransduction Pathway (1269623)
ncbi summary :
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008]
uniprot summary :
Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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