catalog number :
MBS2031035
products type :
Recombinant Protein
products full name :
Recombinant Voltage Dependent Anion Channel Protein 1 (VDAC1)
products short name :
[Voltage Dependent Anion Channel Protein 1]
other names :
[voltage dependent anion channel 1; Mitochondrial outer membrane protein porin 1; voltage dependent anion channel 1; Voltage-dependent anion-selective channel protein 1; AtVDAC1; VDAC-1]
products gene name :
[VDAC1]
other gene names :
[VDAC1; VDAC1; 5076; ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1; ATVDAC1; T22N4.9; T22N4_9; VDAC1; voltage dependent anion channel 1; AtVDAC1; VDAC-1]
uniprot entry name :
VDAC1_ARATH
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300
concentration :
Original Concentration: 200ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control, Immunogen, SDS-PAGE, WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
Sequence Information
image2 heading :
SDS-Page
image3 heading :
Testing Data
other info1 :
Source: Prokaryotic expression. Residuess: Ala2~Ala283. Tags: N-terminal His and GST Tag. Tissue Specificity: Membrane, Mitochondrion. Traits: Freeze-dried powder. Predicted isoelectric point: 8.6. Predicted Molecular Mass: 60.6kDa. Accurate Molecular Mass: 61kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
NP_186777.1
ncbi gb acc num :
NM_110994.3
ncbi summary :
Encodes a voltage-dependent anion channel (VDAC: AT3G01280/VDAC1, AT5G67500/VDAC2, AT5G15090/VDAC3, AT5G57490/VDAC4, AT5G15090/VDAC5). VDACs are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol.
uniprot summary :
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (). Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.