product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Leptin Mouse, Recombinant, E Coli
catalog :
MBS203097
quantity :
0.1 mg
price :
375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203097
products type :
Recombinant Protein
products full name :
Leptin Mouse, Recombinant, E Coli
products short name :
Leptin
products name syn :
LEP; OB; OBS; Leptin Mouse; Obesity factor; Obese protein; Leptin
other names :
leptin; Leptin; leptin; obesity factor; leptin; Obesity factor
other gene names :
Lep; Lep; ob; obese; Ob
uniprot entry name :
LEP_MOUSE
sequence length :
167
sequence :
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
purity :
> 95% by SDS - PAGE
form :
Liquid. In Phosphate buffered saline pH7.4
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Mouse
other info2 :
Expression System: E Coli
products categories :
Hormones & Cytokines
products description :
Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E.coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
products references :
Jeong KJ., et al. (1999) Appl Environ Microbiol. 65(7), 3027-32. Anini Y., et al. (2003) Diabetes. 52(2), 252-259. Hyogo H., et al. (2002) J. Biol. Chem. 277(37), 34117-34124.
ncbi gi num :
6678678
ncbi acc num :
NP_032519
ncbi gb acc num :
NM_008493.3
ncbi mol weight :
16 kDa (147 aa), confirmed by MALDI-TOF.
ncbi pathways :
AMPK Signaling Pathway 989651!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83290!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198299!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Incretin Synthesis, Secretion, And Inactivation Pathway 1110259!!Jak-STAT Signaling Pathway 83274!!Jak-STAT Signaling Pathway 488
size :
0.1 mg
price :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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