product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Prolactin (29-227) Human, Recombinant, E Coli
catalog :
MBS203093
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203093
products type :
Recombinant Protein
products full name :
Prolactin (29-227) Human, Recombinant, E Coli
products short name :
Prolactin
products name syn :
PRL; Prolactin; Lactogenic hormone; Luteotropic hormone; Mammotropin; OTTHuMP00000017727; Prolactin precursor.
other names :
prolactin; Prolactin; prolactin; decidual prolactin; prolactin; N/A
other gene names :
PRL; PRL; PRL
uniprot entry name :
PRL_HUMAN
sequence length :
227
sequence :
MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC
purity :
> 95% by SDS - PAGE
form :
Liquid. In Phosphate buffer saline (pH 7.4)
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Hormones & Cytokines
products description :
Prolactin is a hormone synthesised and secreted by lactotrope cells in the adenohypophysis(anterior pituitary gland). Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation).Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immunoregulation. Prolactin was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
products references :
Ben-jonathan N., et al. (1996) Endocr Rev. 17(6):639-69. Cooke NE., et al. (1981) J. Biol. Chem. 256, 4007-4016. Goffin V., et al. (1999) Mol Cell Endocrinol. 151, 79-87.
ncbi gi num :
4506105
ncbi acc num :
NP_000939
ncbi gb acc num :
NM_000948.5
ncbi mol weight :
23 kDa (200 aa), confirmed by MALDI-TOF.
ncbi pathways :
Amyloids Pathway 366238!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Disease Pathway 530764!!ErbB4 Signaling Events Pathway 137991!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Growth Hormone Receptor Signaling Pathway 477128!!Immune System Pathway 106386!!Jak-STAT Signaling Pathway 83077
ncbi summary :
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
size :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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