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company name :
MyBioSource
product type :
protein
product name :
SNAP-25 (Synaptosomal-associated protein 25kDa), C.elegans Recombinant, expressed in E Coli
catalog :
MBS203012
quantity :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS203012
products type :
Recombinant Protein
products full name :
SNAP-25 (Synaptosomal-associated protein 25kDa), C.elegans Recombinant, expressed in E Coli
products short name :
SNAP-25
products name syn :
SNAP25; SNAP-25; Synaptosomal-associated protein 25kDa; FLJ23079; RIC-4; RIC4; SEC9; SNAP 25; bA416N4.2; dJ1068F16.2; SuP; resistance to inhibitors of cholinesterase 4 homolog; super protein; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein 25; RIC 4
other names :
synaptosomal-associated protein 25 isoform SNAP25A; Synaptosomal-associated protein 25; synaptosomal-associated protein 25; SUP; resistance to inhibitors of cholinesterase 4 homolog; super protein; synaptosomal-associated protein, 25kD; synaptosomal-associated protein, 25kDa; Super protein; SUP; Synaptosomal-associated 25 kDa protein
products gene name :
SNAP-25
other gene names :
SNAP25; SNAP25; RIC4; SEC9; SNAP; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2; SNAP; SNAP-25; SUP
uniprot entry name :
SNP25_HUMAN
sequence length :
206
sequence :
MSGDDDIPEG LEAINLKMNA TTDDSLESTR RMLALCEESK EAGIKTLVML DDQGEQLERC EGALDTINQD MKEAEDHLKG MEKCCGLCVL PWNKTDDFEK TEFAKAWKKD DDGGVISDQP RITVGDSSMG PQGGYITKIT NDAREDEMDE NVQQVSTMVG NLRNMAIDMS TEVSNQNRQL DRIHDKAQSN EVRVESANKR AKNLITK
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl pH7.5, 50mM NaCl, 5mMDTT, 1mM EDTA, 10%Glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human
other info2 :
Expression System: E Coli
products categories :
Neuroscience
products description :
SNAP-25 is a presynaptic plasma membrane protein essential for synaptic vesicle fusion and neurotransmitter release. The membrane proteins SNAP-25, synaptobrevin and syntaxin make up the core complex (SNARE) essential for docking and holding synaptic vesicles at the pre synaptic membrane. SNAP-25 gene was amplified by PCR from C.elegans and cloned into an E. coli expression vector. SNAP-25 was purified by using conventional chromatography techniques.
products references :
Saifee O., et al. (1998) Mol.Biol.Cell 9(6);1235-52. Yang Y., et al. (2000). 275(38);29482-7.
ncbi gi num :
18765733
ncbi acc num :
NP_003072.2
ncbi gb acc num :
NM_003081.3
ncbi mol weight :
23 kDa (207 aa), confirmed by MALDI-TOF.
ncbi pathways :
Acetylcholine Neurotransmitter Release Cycle Pathway 106525!!Disease Pathway 530764!!Dopamine Neurotransmitter Release Cycle Pathway 106523!!Effects Of Botulinum Toxin Pathway 138028!!GABA Synthesis, Release, Reuptake And Degradation Pathway 187174!!Glutamate Neurotransmitter Release Cycle Pathway 106522!!Insulin Signaling Pathway 198845!!Insulin Secretion Pathway 777534!!Integration Of Energy Metabolism Pathway 106096!!Metabolism Pathway 477135
ncbi summary :
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
255 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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