Recombinant Forkhead Box Protein P1 (FOXP1) | MyBioSource MBS2029989 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Forkhead Box Protein P1 (FOXP1)

catalog :

MBS2029989

quantity :

0.01 mg

price :

140 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2029989

products type :

Recombinant Protein

products full name :

Recombinant Forkhead Box Protein P1 (FOXP1)

products short name :

[Forkhead Box Protein P1]

other names :

[forkhead box protein P1 isoform 1; Forkhead box protein P1; forkhead box protein P1; forkhead box P1; Forkhead-related transcription factor 1]

products gene name :

[FOXP1]

other gene names :

[Foxp1; Foxp1; AI461938; AW494214; 3110052D19Rik; 4932443N09Rik]

uniprot entry name :

FOXP1_MOUSE

host :

E.coli

sequence length :

705

sequence :

The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- NAEVRPPFTY ASLIRQAILE SPEKQLTLNE IYNWFTRMFA YFRRNAATWK NAVRHNLSLH KCFVRVENVK GAVWTVDEVE FQKRRPQKIS GNPSLIKNMQ SSHAYCTPLN AALQASMAEN SIPLYTTASM GNPTLGNLAS AIREELNGAM EHTNSNESDS SPGRSPMQAV HPVHVKEEPL DPEEAEGPLS LVTTANHSPDFDHDRDYEDE P

purity :

> 95%

concentration :

Original Concentration: 200 ug/mL

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within theexpiration date under appropriate storage condition.

tested application :

Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). (May be suitable for use in other assays to be determined by the end user.)

image1 heading :

SDS-Page

other info1 :

Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Asn461~Pro671. Tags: N-terminal His Tag. Subcellular Location: Nucleus. Traits: Freeze-dried powder. Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

other info2 :

Predicted isoelectric point: 6.3. Predicted Molecular Mass: 27.3kDa. Accurate Molecular Mass: 33kDa as determined by SDS-PAGE reducing conditions. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows: 1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

ncbi gi num :

16716509

ncbi acc num :

NP_444432.1

ncbi gb acc num :

NM_053202.2

uniprot summary :

FOXP1: Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B-cell development. Forms homodimers and heterodimers with FOXP2 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1. 5 isoforms of the human protein are produced by alternative splicing. Protein type: DNA-binding; Transcription factor; Cell cycle regulation; C2H2-type zinc finger protein. Cellular Component: nucleus. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; metal ion binding; chromatin binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; skeletal muscle development; transcription, DNA-dependent; immunoglobulin V(D)J recombination; in utero embryonic development; positive regulation of transcription, DNA-dependent; heart development; motor axon guidance; sarcomere organization; negative regulation of transcription from RNA polymerase II promoter; cardiac muscle cell differentiation; smooth muscle development; positive regulation of immunoglobulin production; pre-B cell differentiation; embryonic development; regulation of transcription, DNA-dependent; positive regulation of mesenchymal cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of cardiac muscle cell proliferation; negative regulation of transcription, DNA-dependent; positive regulation of epithelial cell proliferation; lung development

size1 :

0.01 mg

price1 :

140 USD

size2 :

0.05 mg

price2 :

255

size3 :

0.1 mg

price3 :

390

size4 :

0.2 mg

price4 :

480

size5 :

0.5 mg

price5 :

935

size6 :

1 mg

price6 :

1380

more info or order :

MyBioSource product webpage