protein

Recombinant Matrix Metalloproteinase 10 (MMP10)

MBS2029751

0.01 mg

150 USD

Recombinant Protein

Recombinant Matrix Metalloproteinase 10 (MMP10)

[Matrix Metalloproteinase 10]

[matrix metalloproteinase 10 (stromelysin 2); Stromelysin-2; stromelysin-2; matrix metallopeptidase 10; Matrix metalloproteinase-10; MMP-10; Transin-2]

[MMP10]

[MMP10; MMP10; SL-2; STMY2; STMY2; SL-2; MMP-10]

MMP10_HUMAN

E Coli

476

>97%

Original Concentration: 200 ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)

SDS-Page

Organism Species: Mus musculus(Mouse). Source: Prokaryotic expression. Residues: Glu154~Ser472. Tags: N-terminal His Tag. Subcellular Location: Secreted, Extracellular matrix. Traits: Freeze-dried powder. Buffer: 100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose. Predicted isoelectric point: 5.7. Predicted Molecular Mass: 39.7kDa. Accurate Molecular Mass: 40kDa as determined by SDS-PAGE reducing conditions.

Usage: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

30583723

AAP36110.1

Activation Of Matrix Metalloproteinases Pathway (1270258); Collagen Degradation Pathway (1270259); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); Matrix Metalloproteinases Pathway (198900)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

MMP10: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Belongs to the peptidase M10A family. Protein type: Protease; Secreted; Secreted, signal peptide; EC 3.4.24.22; Extracellular matrix. Chromosomal Location of Human Ortholog: 11q22.3. Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region. Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding. Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; proteolysis; regulation of cell migration

0.01 mg

150 USD

0.05 mg

285

0.1 mg

445

0.2 mg

550

0.5 mg

1060

1 mg

1580