Recombinant Fucosyltransferase 8 (FUT8) | MyBioSource MBS2029617 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Fucosyltransferase 8 (FUT8)

catalog :

MBS2029617

quantity :

0.01 mg

price :

145 USD

more info or order :

MyBioSource product webpage

image

image 1 :

image 2 :

product information

catalog number :

MBS2029617

products type :

Recombinant Protein

products full name :

Recombinant Fucosyltransferase 8 (FUT8)

products short name :

[Fucosyltransferase 8]

other names :

[fucosyltransferase 8; Alpha-(1,6)-fucosyltransferase; alpha-(1,6)-fucosyltransferase; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Fucosyltransferase 8; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase]

products gene name :

[FUT8]

other gene names :

[FUT8; FUT8; Alpha1-6FucT]

uniprot entry name :

FUT8_HUMAN

host :

E.coli

purity :

> 97%

form :

100mMNaHCO 3 , 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

concentration :

Original Concentration: 200ug/mL

storage stability :

Storage:. Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).

app notes :

(May be suitable for use in other assays to be determined by the end user.)

image1 heading :

Sequence Information

image2 heading :

SDS-Page

other info1 :

Organism Species: Mus musculus (Mouse). Source: Prokaryotic expression. Residues: Lys206~Lys575. Tags: N-terminal His Tag. Subcellular Location: Membrane, Golgi apparatus. Traits: Freeze-dried powder

other info2 :

Predicted isoelectric point: 6.8. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

ncbi gi num :

24421093

ncbi acc num :

CAD55805.1

uniprot acc num :

Q8IUA5

ncbi mol weight :

Predicted Molecular Mass: 46.1kDa. Accurate Molecular Mass: 46kDa as determined by SDS-PAGE reducing conditions.

ncbi pathways :

Asparagine N-linked Glycosylation Pathway (1268714); Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway (82983); Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway (357); Metabolic Pathways (132956); Metabolism Of Proteins Pathway (1268677); N-Glycan Biosynthesis Pathway (82975); N-Glycan Biosynthesis Pathway (345); N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway (1268730); N-glycan Biosynthesis, Complex Type Pathway (413356); N-glycan Biosynthesis, Complex Type Pathway (468278)

ncbi summary :

This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

uniprot summary :

FUT8: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Glycan Metabolism - keratan sulfate biosynthesis; Motility/polarity/chemotaxis; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; EC 2.4.1.68; Transferase. Chromosomal Location of Human Ortholog: 14q24.3. Cellular Component: Golgi membrane; Golgi apparatus; membrane; cytoplasm; integral to membrane. Molecular Function: glycoprotein 6-alpha-L-fucosyltransferase activity; SH3 domain binding. Biological Process: integrin-mediated signaling pathway; cell migration; receptor metabolic process; in utero embryonic development; oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation; respiratory gaseous exchange; post-translational protein modification; GDP-L-fucose metabolic process; cellular protein metabolic process; transforming growth factor beta receptor signaling pathway; protein amino acid N-linked glycosylation via asparagine; protein amino acid glycosylation in Golgi; N-glycan processing; L-fucose catabolic process

size1 :

0.01 mg

price1 :

145 USD

size2 :

0.05 mg

price2 :

280

size3 :

0.1 mg

price3 :

435

size4 :

0.2 mg

price4 :

535

size5 :

0.5 mg

price5 :

1035

size6 :

1 mg

price6 :

1540

more info or order :

MyBioSource product webpage