catalog number :
MBS2028995
products type :
Recombinant Protein
products full name :
Recombinant Secretogranin II (SCG2)
products short name :
[Secretogranin II]
other names :
[secretogranin II; Secretogranin-2; Chromogranin-C; Secretogranin II; SgII]
products gene name :
[SCG2]
other gene names :
[SCG2; CHGC; SgII; SN]
uniprot entry name :
SCG2_HUMAN
sequence :
QRNQLLQKEP DLRLENVQKF PSPEMIRALE YIENLRQQAH KEESSPDYNP YQGVSVPLQQ KENGDESHLP ERDSLSEEDW MRIILEALRQ AENEPQSAPK ENKPYALNSE KNFPMDMSDD YETQQWPERK LKHMQFPPMY EENSRDNPFK RTNEIVEEQY TPQSLATLES VFQELGKLTG PNNQKRERMD EEQKLYTDDE DDIYKANNIA YEDVVGGEDW NPVEEKIESQ TQEEVRDSKE NIEKNEQIND EMKRSGQLGI QEEDLRKESK DQLSDDVSKV IAYLKRLVNA AGSGRLQNGQ NGERATRLFE KPLDSQSIYQ LIEISRNLQI PPEDLIEMLK TGEKPNGSVE PERELDLPVD LDDISEADLD HPDLFQNRML SKSGYPKTPG RAGTEALPDG LSVEDILNLL GMESAANQKT SYFPNPYNQE KVLPRLPYGA GRSRSNQLPK AAWIPHVENR QMAYENLNDK DQELGEYLAR MLVKYPEIIN SNQVKRVPGQ GSSEDDLQEE EQIEQAIKEH LNQGSSQETD KLAPVSKRFP VGPPKNDDTP NRQYWDEDLL MKVLEYLNQE KAEKGREHIA KRAMENM
form :
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
concentration :
Original Concentration: 200ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
app notes :
May be suitable for use in other assays to be determined by the end user.
image1 heading :
Gene Sequencing (Extract)
other info1 :
Organism Species: Homo sapiens (Human). Source: Prokaryotic expression. Residues: Gln31~Met617. Tags: N-terminal His Tag. Subcellular Location: n/a. Traits: Freeze-dried powder
other info2 :
Predicted isoelectric point: 4.7. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ncbi acc num :
AAA36607.1
ncbi mol weight :
Predicted Molecular Mass: 71.5kDa. Accurate Molecular Mass: 72kDa as determined by SDS-PAGE reducing conditions.
uniprot summary :
SCG2: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. Belongs to the chromogranin/secretogranin protein family. Protein type: Cell cycle regulation; Apoptosis; Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2q35-q36. Cellular Component: extracellular space; secretory granule. Molecular Function: chemoattractant activity; cytokine activity; protein binding. Biological Process: angiogenesis; endothelial cell migration; eosinophil chemotaxis; induction of positive chemotaxis; inflammatory response; MAPKKK cascade; negative regulation of endothelial cell proliferation; positive chemotaxis; positive regulation of endothelial cell proliferation; protein secretion