Polyclonal Antibody to Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) | MyBioSource MBS2028735 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)

catalog :

MBS2028735

quantity :

0.01 mg

price :

115 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant CECR1, Human.

image 2 :

DAB staining on IHC-P; Samples: Human Stomach Tissue

image 3 :

DAB staining on IHC-P; Samples: Human Breast Cancer Tissue.

product information

catalog number :

MBS2028735

products type :

Antibody

products full name :

Polyclonal Antibody to Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1)

products short name :

[Cat Eye Syndrome Chromosome Region]

other names :

[adenosine deaminase 2 isoform a; Adenosine deaminase 2; adenosine deaminase 2; adenosine deaminase CECR1; adenosine deaminase 2; Cat eye syndrome critical region protein 1]

products gene name :

[CECR1]

other gene names :

[ADA2; ADA2; PAN; ADGF; CECR1; IDGFL; SNEDS]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

The antibody is a rabbit polyclonal antibody raised against CECR1. It has beenselected for its ability to recognize CECR1 in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples: Human Rectum Cancer Tissue.

image5 heading :

Immunohistochemistry (IHC)

image5 description :

DAB staining on IHC-P; Samples: Human Kidney Tissue.

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CECR1 (Ile30~Lys511) expressed in E.coli.

other info2 :

Conjugate: No Conjugate. Immunogen: Recombinant CECR1 (Ile30~Lys511) expressed in E Coli. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2082778

ncbi gi num :

532691754

ncbi acc num :

NP_001269154.1

ncbi gb acc num :

NM_001282225.1

uniprot acc num :

Q9NZK5

ncbi mol weight :

30,668 Da

ncbi pathways :

Metabolic Pathways (132956); Metabolism Of Proteins Pathway (1268677); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); Surfactant Metabolism Pathway (1309223)

ncbi summary :

This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

uniprot summary :

CECR1: Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. Belongs to the adenosine and AMP deaminases family. ADGF subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.5.4.4; Hydrolase; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 22q11.1. Cellular Component: cytosol; extracellular region; extracellular space. Molecular Function: adenosine deaminase activity; adenosine receptor binding; growth factor activity; heparin binding; protein homodimerization activity; proteoglycan binding; zinc ion binding. Biological Process: adenosine catabolic process; cellular protein metabolic process; hypoxanthine salvage; inosine biosynthetic process; multicellular organism development; neutrophil degranulation. Disease: Polyarteritis Nodosa, Childhood-onset; Sneddon Syndrome

size1 :

0.01 mg

price1 :

115 USD

size2 :

0.02 mg

price2 :

135

size3 :

0.05 mg

price3 :

190

size4 :

0.1 mg

price4 :

245

size5 :

0.2 mg

price5 :

370

size6 :

1 mg

price6 :

880

more info or order :

MyBioSource product webpage