Polyclonal Antibody to Cluster Of Differentiation 276 (CD276) | MyBioSource MBS2028718 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Cluster Of Differentiation 276 (CD276)

catalog :

MBS2028718

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Mouse Serum; Primary Ab: 3ug/ml Rabbit Anti-Mouse CD276 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

image 2 :

Western Blot: Sample: Recombinant protein.

image 3 :

DAB staining on fromalin fixed paraffin-embedded Ovary tissue)

product information

catalog number :

MBS2028718

products type :

Antibody

products full name :

Polyclonal Antibody to Cluster Of Differentiation 276 (CD276)

products short name :

[Cluster Of Differentiation 276]

other names :

[CD276 antigen; CD276 antigen; CD276 antigen; CD276 antigen; B7 homolog 3; B7-H3; Costimulatory molecule; CD_antigen: CD276]

products gene name :

[CD276]

other gene names :

[Cd276; Cd276; B7h3; B7RP-2; AU016588; 6030411F23Rik; B7h3; B7-H3]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

1 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB), Immunohistochemistry(IHC), Immunocytochemistry (ICC),Immunoprecipitaion (IP).

app notes :

Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CD276 (Thr47~Gly213) expressed in E.coli

ncbi gi num :

19527206

ncbi acc num :

NP_598744.1

ncbi gb acc num :

NM_133983.4

uniprot acc num :

Q8VE98

ncbi pathways :

Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480)

uniprot summary :

CD276: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Belongs to the immunoglobulin superfamily. BTN/MOG family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 9 9 B. Cellular Component: external side of plasma membrane; integral component of membrane; membrane. Molecular Function: receptor binding. Biological Process: negative regulation of inflammatory response; negative regulation of interferon-gamma biosynthetic process; negative regulation of interleukin-2 biosynthetic process; negative regulation of T cell proliferation; positive regulation of bone mineralization; positive regulation of interferon-gamma biosynthetic process; positive regulation of osteoblast differentiation; positive regulation of T cell proliferation; regulation of immune response; T cell activation

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

170

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

315

size6 :

1 mg

price6 :

745

more info or order :

MyBioSource product webpage