catalog number :
MBS2028688
products full name :
Polyclonal Antibody to Defensin Alpha 1, Neutrophil (DEFa1)
products short name :
[Defensin Alpha 1]
other names :
[alpha-defensin 1; Alpha-defensin 1; alpha-defensin 1; defensin, alpha 1; Cryptdin-1; Defensin-related cryptdin peptide]
products gene name :
[DEFa1]
other gene names :
[Defa1; Defa1; Defcr; Defcr1; Defcr; Defcr1]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.79 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:400-1600. Immunohistochemistry: 5-20 ug/mL;1:40-160. Immunocytochemistry: 5-20 ug/mL;1:40-160. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant DEFa1 (Asp20~Arg93) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2058132
ncbi acc num :
NP_034161.2
ncbi gb acc num :
NM_010031.2
uniprot summary :
defensin, alpha 1: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. Belongs to the alpha-defensin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8 A2 8. Cellular Component: extracellular region; extracellular space. Biological Process: defense response; defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; response to drug