product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Epiregulin (EREG)
catalog :
MBS2028562
quantity :
0.01 mg
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2028562 image 1
Western Blot: Sample: Recombinant EREG Human.
image 2 :
MyBioSource MBS2028562 image 2
DAB staining on IHC-P; Samples: Rat Stomach Tissue.
image 3 :
MyBioSource MBS2028562 image 3
DAB staining on IHC-P; Samples: Rat Stomach Tissue)
product information
catalog number :
MBS2028562
products type :
Antibody
products full name :
Polyclonal Antibody to Epiregulin (EREG)
products short name :
[Epiregulin]
other names :
[proepiregulin preproprotein; Proepiregulin; proepiregulin; epiregulin]
products gene name :
[EREG]
other gene names :
[Ereg; Ereg; EPR]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol
concentration :
1 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Rattus norvegicus (Rat). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant EREG (Met1~Val162) expressed in E.coli
ncbi gi num :
11078689
ncbi acc num :
NP_067721.1
ncbi gb acc num :
NM_021689.1
uniprot acc num :
Q9Z0L5
ncbi pathways :
ARMS-mediated Activation Pathway (1376921); Adaptive Immune System Pathway (1377120); Axon Guidance Pathway (1376511); Cytokine Signaling In Immune System Pathway (1377233); DAP12 Interactions Pathway (1377220); DAP12 Signaling Pathway (1377221); Developmental Biology Pathway (1376510); Downregulation Of ERBB2 Signaling Pathway (1457898); Downstream Signal Transduction Pathway (1376932); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (1377134)
ncbi summary :
may play a role in vascular smooth muscle cell proliferation and vascular remodeling stimulated by vasoactive agonists [RGD, Feb 2006]
uniprot summary :
Epiregulin: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 14p22. Cellular Component: extracellular space; integral component of membrane; plasma membrane. Molecular Function: epidermal growth factor receptor binding; growth factor activity. Biological Process: angiogenesis; cell proliferation; cell-cell signaling; cytokine-mediated signaling pathway; epidermal growth factor receptor signaling pathway; female meiotic nuclear division; keratinocyte proliferation; luteinizing hormone signaling pathway; mRNA transcription; negative regulation of cell proliferation; negative regulation of smooth muscle cell differentiation; negative regulation of transcription, DNA-dependent; oocyte maturation; ovarian cumulus expansion; ovulation; positive regulation of angiogenesis; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of cytokine biosynthetic process; positive regulation of cytokine production; positive regulation of DNA replication; positive regulation of epidermal growth factor-activated receptor activity; positive regulation of fibroblast proliferation; positive regulation of innate immune response; positive regulation of interleukin-6 biosynthetic process; positive regulation of mitotic nuclear division; positive regulation of phosphorylation; positive regulation of protein kinase activity; positive regulation of smooth muscle cell proliferation; primary follicle stage; response to peptide hormone
size1 :
0.01 mg
price1 :
110 USD
size2 :
0.02 mg
price2 :
130
size3 :
0.05 mg
price3 :
185
size4 :
0.1 mg
price4 :
230
size5 :
0.2 mg
price5 :
350
size6 :
1 mg
price6 :
830
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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