catalog number :
MBS2028114
products full name :
Polyclonal Antibody to Acidic Salivary Proline Rich Phosphoprotein 2 (PRH2)
products short name :
[Acidic Salivary Proline Rich Phosphoprotein 2]
other names :
[salivary acidic proline-rich phosphoprotein 1/2 preproprotein; Salivary acidic proline-rich phosphoprotein 1/2; salivary acidic proline-rich phosphoprotein 1/2; proline rich protein HaeIII subfamily 2; Db-s; PRP-1/PRP-2; Parotid acidic protein; Pa]
products gene name :
[PRH2]
other gene names :
[PRH2; PRH1; Pr; pr1/Pr2; PRP-1/PRP-2; Pa; PIF-S]
specificity :
The antibody is a Rabbit polyclonal antibody raised against PRH2. It has been selected for its ability to recognize PRH2 in immunohistochemical staining and western blotting.
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were
observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM
app notes :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant PRH2 (Asp17~Gln166) expressed in E.coli.
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2073041
ncbi acc num :
NP_001103683.1
ncbi gb acc num :
NM_001110213.1
ncbi mol weight :
17,016 Da
ncbi pathways :
Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352)
ncbi summary :
This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]
uniprot summary :
PRH: PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth. Protein type: Inhibitor. Chromosomal Location of Human Ortholog: 12p13.2. Cellular Component: extracellular space. Molecular Function: protein binding