catalog number :
MBS2028029
products full name :
Polyclonal Antibody to Surfactant Associated Protein D (SPD)
products short name :
[Surfactant Associated Protein D]
other names :
[pulmonary surfactant-associated protein D; Pulmonary surfactant-associated protein D; pulmonary surfactant-associated protein D; surfactant associated protein D; Lung surfactant protein D]
products gene name :
[SPD]
other gene names :
[Sftpd; Sftpd; SP-D; Sfpd; Sftp4; AI573415; Sftp4; PSP-D; SP-D]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
0.25mg/ml
storage stability :
Storage:. Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-30ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid
other info2 :
Immunogen: Recombinant SPD (Val259~Phe374 (Accession # P50404)) expressed in E.coli. ( MBS2031572 )
ncbi acc num :
NP_033186.1
ncbi gb acc num :
NM_009160.2
ncbi pathways :
Metabolism Of Proteins Pathway (1367207); Phagosome Pathway (153914); Phagosome Pathway (153859); Surfactant Metabolism Pathway (1367290)
uniprot summary :
SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14 B 14 22.36 cM. Cellular Component: collagen; cytoplasm; cytoplasmic vesicle; extracellular region; extracellular space; multivesicular body; proteinaceous extracellular matrix; rough endoplasmic reticulum. Molecular Function: carbohydrate binding; identical protein binding; lipopolysaccharide binding; monosaccharide binding. Biological Process: alveolus development; immune system process; induction of bacterial agglutination; innate immune response; negative regulation by host of symbiont molecular function; negative regulation of interleukin-2 production; negative regulation of phagocytosis; negative regulation of T cell proliferation; opsonization; positive regulation of phagocytosis; regulation of liquid surface tension; respiratory gaseous exchange; surfactant homeostasis