catalog number :
MBS2028020
products full name :
Polyclonal Antibody to FMS Like Tyrosine Kinase 3 Ligand (Flt3L)
products short name :
[FMS Like Tyrosine Kinase 3]
other names :
[fms-related tyrosine kinase 3 ligand; Fms-related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; SL cytokine]
products gene name :
[Flt3L]
other gene names :
[Flt3l; Flt3lg; Ly72L; Flt3lg; Flt3l; Flt3 ligand; Flt3L]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.83 mg/ml
storage stability :
Storage:. Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB),Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant Flt3L (Gly27~Gln189) expressed in E.coli ( MBS2029390 )
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog # MBS2035717
ncbi acc num :
NP_038548.3
ncbi gb acc num :
NM_013520.3
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489); Pathways In Cancer (83298)
uniprot summary :
FLT3LG: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Ligand, receptor tyrosine kinase; Membrane protein, integral. Chromosomal Location of Human Ortholog: 7 B3 7 29.14 cM. Cellular Component: cell surface; extracellular region; extracellular space; integral component of membrane; membrane; plasma membrane. Molecular Function: cytokine activity; protein homodimerization activity; receptor tyrosine kinase binding. Biological Process: embryonic hemopoiesis; homeostasis of number of cells within a tissue; lymphocyte differentiation; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of myoblast differentiation; positive regulation of natural killer cell differentiation; positive regulation of protein phosphorylation; positive regulation of transcription from RNA polymerase II promoter; regulation of myeloid dendritic cell activation