Polyclonal Antibody to Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1) | MyBioSource MBS2028019 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1)

catalog :

MBS2028019

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant protein.

image 2 :

DAB staining on fromalin fixed paraffin- embedded Kidney tissue)

product information

catalog number :

MBS2028019

products type :

Antibody

products full name :

Polyclonal Antibody to Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1)

products short name :

[Latent Transforming Growth Factor Beta Binding Protein 1]

other names :

[latent-transforming growth factor beta-binding protein 1 isoform LTBP-1S; Latent-transforming growth factor beta-binding protein 1; latent-transforming growth factor beta-binding protein 1; latent transforming growth factor beta binding protein 1; Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1]

products gene name :

[LTBP1]

other gene names :

[LTBP1; LTBP1; LTBP-1; TGF-beta1-BP-1]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

0.34 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB),Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).

app notes :

Western blotting: 0.5-2 ug/mL;1:170-700. Immunohistochemistry: 5-20 ug/mL;1:17-70. Immunocytochemistry: 5-20 ug/mL;1:17-70. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant LTBP1 (Asp1424~Glu1721) expressed in E.coli

other info2 :

Conjugate: No Conjugate. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2063426

ncbi gi num :

261337167

ncbi acc num :

NP_000618.3

ncbi gb acc num :

NM_000627.3

uniprot acc num :

Q14766

ncbi pathways :

Elastic Fibre Formation Pathway (730310); Extracellular Matrix Organization Pathway (576262); Integrated Pancreatic Cancer Pathway (711360); Molecules Associated With Elastic Fibres Pathway (730311); TGF Beta Signaling Pathway (198810); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)

ncbi summary :

The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

uniprot summary :

LTBP1: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Belongs to the LTBP family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Chaperone; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2p22.3. Cellular Component: endoplasmic reticulum lumen; extracellular matrix; extracellular region; extracellular space; microfibril; protein complex; proteinaceous extracellular matrix. Molecular Function: calcium ion binding; microfibril binding; protein binding; transforming growth factor beta binding; transforming growth factor beta-activated receptor activity. Biological Process: cellular protein metabolic process; post-translational protein modification; transmembrane receptor protein serine/threonine kinase signaling pathway

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

130

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

340

size6 :

1 mg

price6 :

800

more info or order :

MyBioSource product webpage