catalog number :
MBS2027849
products full name :
Polyclonal Antibody to Defensin Alpha 4, Corticostatin (DEFa4)
products short name :
[Defensin Alpha 4]
other names :
[alpha-defensin 4; Alpha-defensin 4; alpha-defensin 4; defensin, alpha, 4; Defensin-related cryptdin-4]
products gene name :
[DEFa4]
other gene names :
[Defa4; Defa4; Crp4; Defa28; Defcr4; Defcr4]
sequence :
Antigen: The target protein is fused with two N-terminal Tags, His-tag and GST-tag and its sequence is listed below. MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTGGG SGIEGRGSMG YRGSEF-D PIQNTDEETK TEEQPGEEDQ AVSISFGGQE GSALHEKSLR GLLCYCRKGH CKRGERVRGT CGIRFLYCCP
specificity :
The antibody is a rabbit polyclonal antibody raised against DEFa4. It has beenselected for its ability to recognize DEFa4 in immunohistochemical staining andwestern blotting.
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
0.75mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2ug/mL;1:350-1500. Immunohistochemistry: 5-20ug/mL;1:35-150. Immunocytochemistry: 5-20ug/mL;1:35-150. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid
other info2 :
Immunogen: Recombinant DEFa4 (Asp20~Arg92 (Accession # P28311)) expressed in E.coli
ncbi acc num :
NP_034169.2
ncbi gb acc num :
NM_010039.2
ncbi mol weight :
10,272 Da
uniprot summary :
DEFA4: Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production. Belongs to the alpha-defensin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8 8 A2. Cellular Component: extracellular region; extracellular space. Molecular Function: phospholipid binding. Biological Process: antibacterial humoral response; defense response; defense response to bacterium; killing of cells of other organism; membrane disruption in other organism