product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Amphiregulin (AREG)
catalog :
MBS2027845
quantity :
0.01 mg
price :
115 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
Bos grunniens mutus
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2027845 image 1
Western Blot: Sample: Recombinant protein.
product information
catalog number :
MBS2027845
products type :
Antibody
products full name :
Polyclonal Antibody to Amphiregulin (AREG)
products short name :
[Amphiregulin]
other names :
[amphiregulin; Amphiregulin; amphiregulin; Amphiregulin]
products gene name :
[AREG]
other gene names :
[AREG; M91_08174]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
concentration :
0.84mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2 ug/mL;1:400-1600. Immunohistochemistry: 5-20 ug/mL;1:40-160. Immunocytochemistry: 5-20 ug/mL;1:40-160. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Bos taurus; Bovine (Cattle). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant AREG (Leu27~Ala247) expressed in E.coli
ncbi gi num :
555958396
ncbi acc num :
XP_005891318.1
ncbi gb acc num :
XM_005891256.1
uniprot acc num :
L8IUA9
ncbi pathways :
ErbB Signaling Pathway (914665); ErbB Signaling Pathway (458); Hippo Signaling Pathway (914701); Hippo Signaling Pathway (750388)
ncbi summary :
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
uniprot summary :
AREG: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. Belongs to the amphiregulin family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cell surface; cytoplasm; integral to membrane; nucleus. Molecular Function: protein binding; growth factor activity; cytokine activity; epidermal growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; response to peptide hormone stimulus; response to cAMP; response to glucocorticoid stimulus; response to estradiol stimulus; glial cell proliferation; G-protein coupled receptor protein signaling pathway; cell proliferation; cell-cell signaling; response to hydrogen peroxide; positive regulation of cell proliferation; negative regulation of osteoblast differentiation; positive regulation of DNA replication; neurite development; positive regulation of phosphorylation
size1 :
0.01 mg
price1 :
115 USD
size2 :
0.02 mg
price2 :
135
size3 :
0.05 mg
price3 :
190
size4 :
0.1 mg
price4 :
245
size5 :
0.2 mg
price5 :
365
size6 :
1 mg
price6 :
865
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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