catalog number :
MBS2027631
products full name :
Polyclonal Antibody to Surfactant Associated Protein A (SPA)
products short name :
[Surfactant Associated Protein A]
other names :
[Pulmonary surfactant-associated protein A; Pulmonary surfactant-associated protein A; pulmonary surfactant-associated protein A; surfactant associated protein A1]
products gene name :
[SPA]
other gene names :
[Sftpa1; Sftpa1; SP-A; Sftp1; Sftp-1; Sftp-1; Sftp1; Sftpa; PSAP; PSP-A; SP-A]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage:. Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid
other info2 :
Immunogen: Recombinant SFTPA1 (Asn21~Phe248) expressed in E.coli ( MBS2029143 ).
ncbi pathways :
Pertussis Pathway (218112); Pertussis Pathway (218099); Phagosome Pathway (153914); Phagosome Pathway (153859)
uniprot summary :
SFTPA2: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF). Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease. Belongs to the SFTPA family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14 B 14 22.36 cM. Cellular Component: cytoplasmic vesicle; extracellular space; multivesicular body; rough endoplasmic reticulum. Biological Process: opsonization; positive regulation of phagocytosis