catalog number :
MBS2027536
products full name :
Polyclonal Antibody to Chemokine C-Motif Receptor 1 (XCR1)
products short name :
[Chemokine C-Motif Receptor 1]
other names :
[Chemokine XC receptor 1; Chemokine XC receptor 1; chemokine XC receptor 1; chemokine (C motif) receptor 1; Lymphotactin receptor; SCM1 receptor; XC chemokine receptor 1; mXCR1]
products gene name :
[XCR1]
other gene names :
[Xcr1; Xcr1; Gpr5; mXcr1; Ccxcr1; Ccxcr1]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant XCR1 (Thr244~Tyr322) expressed in E.coli
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (575428); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (575426); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); G Alpha (q) Signalling Events Pathway (575456); GPCR Downstream Signaling Pathway (575452); GPCR Ligand Binding Pathway (575425); GPCRs, Other Pathway (198282)
uniprot summary :
XCR1: Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR. Chromosomal Location of Human Ortholog: 9 F4 9 74.71 cM. Cellular Component: cell. Biological Process: chemotaxis; release of sequestered calcium ion into cytosol; response to cytokine