Polyclonal Antibody to Neuropilin 2 (NRP2) | MyBioSource MBS2027380 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Neuropilin 2 (NRP2)

catalog :

MBS2027380

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant protein.

image 2 :

DAB staining on fromalin fixed paraffin-embedded ovary tissue)

image 3 :

DAB staining on IHC-P; Samples: Human Prostate Tissue)

product information

catalog number :

MBS2027380

products type :

Antibody

products full name :

Polyclonal Antibody to Neuropilin 2 (NRP2)

products short name :

[Neuropilin 2]

other names :

[neuropilin-2 isoform 2; Neuropilin-2; neuropilin-2; neuropilin 2; Vascular endothelial cell growth factor 165 receptor 2]

products gene name :

[NRP2]

other gene names :

[NRP2; NRP2; NP2; NPN2; PRO2714; VEGF165R2; VEGF165R2]

clonality :

Polyclonal

host :

Rabbit

purity :

Antige-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

0.45 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-2 ug/mL;1:220-900. Immunohistochemistry: 5-20 ug/mL;1:22-90. Immunocytochemistry: 5-20 ug/mL;1:22-90 . Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant NRP2 (Gly231~Val490) expressed in E.coli

other info2 :

Conjugate: No Conjugate. Immunogen: Recombinant NRP2 (Gly231~Val490) expressed in E Coli. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2069615

ncbi gi num :

41872533

ncbi acc num :

NP_003863.2

ncbi gb acc num :

NM_003872.2

uniprot acc num :

O60462

ncbi pathways :

Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); L1CAM Interactions Pathway (161003); Neurophilin Interactions With VEGF And VEGFR Pathway (106509); NrCAM Interactions Pathway (161009); Signal Transduction Pathway (477114); Signaling By VEGF Pathway (106506); Signaling Events Mediated By VEGFR1 And VEGFR2 Pathway (137940); VEGF Ligand-receptor Interactions Pathway (106507); VEGFR1 Specific Signals Pathway (137924)

ncbi summary :

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc. Chromosomal Location of Human Ortholog: 2q33.3. Cellular Component: extracellular region; integral component of membrane; membrane; plasma membrane. Molecular Function: cytokine binding; growth factor binding; heparin binding; metal ion binding; protein binding; receptor activity; semaphorin receptor activity; vascular endothelial growth factor-activated receptor activity. Biological Process: angiogenesis; axon extension involved in axon guidance; axon guidance; cell adhesion; nerve development; outflow tract septum morphogenesis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; semaphorin-plexin signaling pathway involved in neuron projection guidance; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor signaling pathway

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

130

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

340

size6 :

1 mg

price6 :

800

more info or order :

MyBioSource product webpage