catalog number :
MBS2027266
products full name :
Polyclonal Antibody to Interferon Inducible T-Cell Alpha Chemoattractant (ITaC)
products short name :
[Interferon Inducible T-Cell Alpha Chemoattractant]
other names :
[C-X-C motif chemokine 11; C-X-C motif chemokine 11; C-X-C motif chemokine 11; chemokine (C-X-C motif) ligand 11; Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11]
products gene name :
[ITaC]
other gene names :
[Cxcl11; Cxcl11; Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11; Scyb9b; betaR1; Scyb11; I-TAC]
specificity :
The antibody is a Rabbit polyclonal antibody raised against ITaC. It has been selected for its ability to recognize ITaC in immunohistochemical staining and western blotting.
purity :
Antigen-specific affinity chromatography followed by Protein A affinity
form :
Supplied as a solution form in 0.01M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
storage stability :
Storage: Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant ITaC (Phe22~Met100 (Accession # Q9JHH5)) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2062738
ncbi acc num :
NP_062367.1
ncbi gb acc num :
NM_019494.1
ncbi mol weight :
11,266 Da
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (1110501); Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1110499); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1111486); Disease Pathway (1111319); G Alpha (i) Signalling Events Pathway (1110530)
uniprot summary :
CXCL11: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. Belongs to the intercrine alpha (chemokine CxC) family. Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5 5 E2