catalog number :
MBS2027189
products full name :
Polyclonal Antibody to Lipopolysaccharide Binding Protein (LBP)
products short name :
[Lipopolysaccharide]
other names :
[Lipopolysaccharide-binding protein; Lipopolysaccharide-binding protein; lipopolysaccharide-binding protein; lipopolysaccharide binding protein]
products gene name :
[LBP]
other gene names :
[Lbp; Lbp; Bpifd2; LBP]
specificity :
The antibody is a Rabbit polyclonal antibody raised against LBP. It has been selected for its ability to recognize LBP in immunohistochemical staining and western blotting.
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2µg/mL. Immunohistochemistry: 5-20µg/mL. Immunocytochemistry: 5-20µg/mL. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant LBP (Asn27~Val481) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2054871
ncbi mol weight :
53,600 Da
ncbi pathways :
Immune System Pathway (1377119); Innate Immune System Pathway (1377149); NF-kappa B Signaling Pathway (634541); NF-kappa B Signaling Pathway (634652); Regulation Of TLR By Endogenous Ligand Pathway (1427700); Salmonella Infection Pathway (375168); Salmonella Infection Pathway (375149); Toll Like Receptor 4 (TLR4) Cascade Pathway (1377176); Toll-Like Receptors Cascades Pathway (1377150); Toll-like Receptor Signaling Pathway (83468)
ncbi summary :
binds lipopolysaccharide on outer membrane of gram negative bacteria; involved in immune response [RGD, Feb 2006]
uniprot summary :
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.