catalog number :
MBS2027186
products full name :
Polyclonal Antibody to Integrin Alpha X (ITGaX)
products short name :
[Integrin Alpha X]
other names :
[integrin alpha-X; Integrin alpha-X; integrin alpha-X; integrin alpha X; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c]
products gene name :
[ITGaX]
other gene names :
[Itgax; Itgax; Cr4; N418; Cd11c; AI449405]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.35 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2) Ug/mL;1:170-700. Immunohistochemistry: 5-20) Ug/mL;1:17-70. Immunocytochemistry: 5-20) Ug/mL;1:17-70.
Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Mus musculus. Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CD11c (Arg907~Val1115) expressed in E.coli
ncbi acc num :
NP_067309.1
ncbi gb acc num :
NM_021334.2
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (1110059); ECM Proteoglycans Pathway (1110314); Extracellular Matrix Organization Pathway (1110302); Focal Adhesion Pathway (198353); Hemostasis Pathway (1110026); Integrin Cell Surface Interactions Pathway (1110318); Integrin-mediated Cell Adhesion Pathway (198372); Regulation Of Actin Cytoskeleton Pathway (83286); Regulation Of Actin Cytoskeleton Pathway (500); Tuberculosis Pathway (213781)
uniprot summary :
ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 7 7 F3. Cellular Component: cell surface; external side of plasma membrane; integral component of membrane; integrin complex; membrane. Molecular Function: metal ion binding. Biological Process: activated T cell proliferation; cell adhesion; defense response to virus; heterotypic cell-cell adhesion; integrin-mediated signaling pathway