catalog number :
MBS2027146
products full name :
Polyclonal Antibody to Interleukin 4 (IL4)
products short name :
[Interleukin 4]
other names :
[interleukin-4; Interleukin-4; interleukin-4; interleukin 4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1]
products gene name :
[IL4]
other gene names :
[IL4; IL4; IL-4; IL-4; BSF-1]
specificity :
The antibody is a rabbit polyclonal antibody raised against IL4. It has beenselected for its ability to recognize IL4 in immunohistochemical staining andwestern blotting.
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
app notes :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant IL4 (Gly24~His132) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2036958
ncbi acc num :
NP_001003159.1
ncbi gb acc num :
NM_001003159.1
ncbi mol weight :
15,267 Da
ncbi pathways :
Allograft Rejection Pathway (84169); Allograft Rejection Pathway (535); Asthma Pathway (84166); Asthma Pathway (532); Autoimmune Thyroid Disease Pathway (84167); Autoimmune Thyroid Disease Pathway (533); Cytokine-cytokine Receptor Interaction Pathway (84101); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198591); Fc Epsilon RI Signaling Pathway (84132)
uniprot summary :
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.