Polyclonal Antibody to Cathepsin G (CTSG) | MyBioSource MBS2026814 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Cathepsin G (CTSG)

catalog :

MBS2026814

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Human MCF7 Cells.

image 2 :

Western Blot: Sample: Recombinant CTSG, Human.

image 3 :

DAB staining on IHC-P; Samples: Human Lung Cancer Tissue.

product information

catalog number :

MBS2026814

products type :

Antibody

products full name :

Polyclonal Antibody to Cathepsin G (CTSG)

products short name :

[Cathepsin G]

other names :

[cathepsin G preproprotein; Cathepsin G; cathepsin G; cathepsin G]

products gene name :

[CTSG]

other gene names :

[CTSG; CTSG; CG; CATG; CG]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Homo sapiens (Human)

sequence length :

specificity :

The antibody is a rabbit polyclonal antibody raised against CTSG. It has beenselected for its ability to recognize CTSG in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.

concentration :

0.46mg/ml

storage stability :

Storage:Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determinedby accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and noobvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-2 Ug/mL;1:200-900. Immunohistochemistry: 5-20 Ug/mL;1:20-90. Immunocytochemistry: 5-20 Ug/mL;1:20-90. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples: Human Stomach Tissue

image5 heading :

Immunohistochemistry (IHC)

image5 description :

DAB staining on IHC-P; Samples: Human Kidney Tissue.

other info1 :

. Source: Polyclonal antibody preparation . Fragment: CTSG (Ile21~Leu255). Organism Species: Homo sapiens (Human). Traits: Liquid

other info2 :

Immunogen: Recombinant CTSG (Ile21~Leu255) expressed in E.coli . Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2073780

ncbi gi num :

4503149

ncbi acc num :

NP_001902.1

ncbi gb acc num :

NM_001911.2

uniprot acc num :

P08311

ncbi mol weight :

28,837 Da

ncbi pathways :

ACE Inhibitor Pathway (198763); Activation Of Matrix Metalloproteinases Pathway (576264); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Lysosome Pathway (99052); Lysosome Pathway (96865); Metabolism Of Angiotensinogen To Angiotensins Pathway (685555); Metabolism Of Proteins Pathway (106230)

ncbi summary :

The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]

uniprot summary :

CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family. Protein type: EC 3.4.21.20; Motility/polarity/chemotaxis; Protease. Chromosomal Location of Human Ortholog: 14q12. Cellular Component: cell surface; extracellular matrix; extracellular region; extracellular space; nucleus; plasma membrane; secretory granule; stress granule. Molecular Function: heparin binding; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: angiotensin maturation; antibacterial humoral response; antimicrobial humoral response; cellular protein metabolic process; defense response to fungus; defense response to Gram-negative bacterium; extracellular matrix disassembly; immune response; neutrophil degranulation; positive regulation of immune response; protein amino acid phosphorylation; proteolysis

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

130

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

340

size6 :

1 mg

price6 :

800

more info or order :

MyBioSource product webpage