Polyclonal Antibody to Polyamine Oxidase (PAOX) | MyBioSource MBS2026812 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Polyamine Oxidase (PAOX)

catalog :

MBS2026812

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Mouse Pancreas Tissue.

image 2 :

Western Blot: Sample: Recombinant PAOX, Mouse.

image 3 :

DAB staining on IHC-P; Samples: Mouse Testis Tissue.

product information

catalog number :

MBS2026812

products type :

Antibody

products full name :

Polyclonal Antibody to Polyamine Oxidase (PAOX)

products short name :

[Polyamine Oxidase]

other names :

[peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N(1)-acetyl-spermine/spermidine oxidase; polyamine oxidase (exo-N4-amino); Polyamine oxidase]

products gene name :

[PAOX]

other gene names :

[Paox; Paox; Pao; AI118225; 2410012F02Rik; Pao]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse

sequence :

Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- I ERTREFLNES ETPMASVGEF LKKEISQQVA SWTEDDEDTR KRKLAILNTF FNIECCVSGT HSMDLVALAP FGEYTVLPGL DCILAGGYQG LTDRILASLP KDTVAFDKPV KTIHWNGSFQ EAAFPGETFP VLVECEDGAR LPAHHVIVTV PLGFLKEHQD TFFEPPLPAK KAEAIKKLGF GTNNKIFLEF EEPFWEPDCQ

specificity :

The antibody is a rabbit polyclonal antibody raised against PAOX. It has beenselected for its ability to recognize PAOX in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-5ug/mL. Immunocytochemistry in formalin fixed cells: 5-20ug/mL. Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL. Immunohistochemistry in paraffin section: 5-20ug/mL. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid

other info2 :

Immunogen: Recombinant PAOX (Ile130~Lys356) expressed in E.coli. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2078669

ncbi gi num :

28173566

ncbi acc num :

NP_722478.2

ncbi gb acc num :

NM_153783.4

uniprot acc num :

Q8C0L6

ncbi mol weight :

25,262 Da

ncbi pathways :

Amine Oxidase Reactions Pathway (1367868); Biological Oxidations Pathway (1367854); Interconversion Of Polyamines Pathway (1367829); Metabolism Pathway (1367614); Metabolism Of Amino Acids And Derivatives Pathway (1367816); Metabolism Of Polyamines Pathway (1367827); PAOs Oxidise Polyamines To Amines Pathway (1367870); Peroxisome Pathway (131230); Peroxisome Pathway (131126); Phase 1 - Functionalization Of Compounds Pathway (1367855)

uniprot summary :

PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine N(1),N(12)-diacylspermine spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.5.3.13; Oxidoreductase. Chromosomal Location of Human Ortholog: 7 7 F4. Cellular Component: cytoplasm; peroxisomal matrix; peroxisome. Molecular Function: oxidoreductase activity; polyamine oxidase activity; receptor binding. Biological Process: polyamine catabolic process; putrescine biosynthetic process; putrescine catabolic process; spermidine catabolic process; spermine catabolic process

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

130

size3 :

0.05 mg

price3 :

185

size4 :

0.1 mg

price4 :

230

size5 :

0.2 mg

price5 :

345

size6 :

1 mg

price6 :

825

more info or order :

MyBioSource product webpage