Polyclonal Antibody to C-Type Natriuretic Peptide (CNP) | MyBioSource MBS2026757 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to C-Type Natriuretic Peptide (CNP)

catalog :

MBS2026757

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant CNP, Mouse.

image 2 :

DAB staining on IHC-P; Samples: Mouse Brain Tissue.

image 3 :

DAB staining on IHC-P; Samples: Mouse Brain Tissue)

product information

catalog number :

MBS2026757

products type :

Antibody

products full name :

Polyclonal Antibody to C-Type Natriuretic Peptide (CNP)

products short name :

[C-Type Natriuretic Peptide]

other names :

[C-type natriuretic peptide preproprotein; C-type natriuretic peptide; C-type natriuretic peptide; natriuretic peptide type C]

products gene name :

[CNP]

other gene names :

[Nppc; Nppc; CNP; lbab; Cnp]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mus musculus (Mouse)

specificity :

The antibody is a Rabbit polyclonal antibody raised against CNP. It has been selected for its ability to recognize CNP in immunohistochemical staining and western blotting.

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

0.76mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-2( Ug/mL;1:350-1500. Immunohistochemistry: 5-20(Ug/mL;1:35-150. Immunocytochemistry: 5-20(g/mL;1:35-150. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

. Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CNP (Lys30~Cys126 (Accession # Q61839)) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2046571

ncbi gi num :

6754880

ncbi acc num :

NP_035063.1

ncbi gb acc num :

NM_010933.5

uniprot acc num :

Q61839

ncbi mol weight :

13,320 Da

ncbi pathways :

Cardiac Conduction Pathway (1323440); Muscle Contraction Pathway (1323437); Physiological Factors Pathway (1323447)

ncbi summary :

This gene encodes a member of the natriuretic peptide family. Natriuretic peptides are involved in the control of blood pressure, extracellular fluid volume and electrolyte homeostasis. The encoded protein also plays a role in sensory neuron bifurcation, and is a critical regulator of endochondral bone growth. The encoded protein is a ligand for the natriuretic peptide receptor B, and is synthesized as a preprohormone which is cleaved to produce a mature peptide. Mutations in this gene are associated with dwarfism resulting from impaired endochondral ossification. [provided by RefSeq, Apr 2011]

uniprot summary :

NPPC: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family. Protein type: Hormone; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1 C5 1 43.98 cM. Cellular Component: extracellular region; extracellular space; protein complex; secretory granule. Molecular Function: hormone activity; neuropeptide hormone activity; peptide hormone receptor binding; protein homodimerization activity; receptor binding. Biological Process: animal organ development; cGMP biosynthetic process; negative regulation of cell proliferation; negative regulation of DNA metabolic process; negative regulation of meiotic cell cycle; ossification; positive regulation of cGMP biosynthetic process; positive regulation of osteoblast differentiation; post-embryonic development; protein folding; receptor guanylyl cyclase signaling pathway; regulation of blood vessel size; regulation of cAMP metabolic process; regulation of cGMP metabolic process; regulation of multicellular organism growth; reproductive process

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

170

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

315

size6 :

1 mg

price6 :

745

more info or order :

MyBioSource product webpage