Polyclonal Antibody to Carnitine Acetyltransferase (CRAT) | MyBioSource MBS2026731 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Carnitine Acetyltransferase (CRAT)

catalog :

MBS2026731

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant CRAT, Human.

image 2 :

DAB staining on fromalin fixed paraffin-embedded testis tissue)

product information

catalog number :

MBS2026731

products type :

Antibody

products full name :

Polyclonal Antibody to Carnitine Acetyltransferase (CRAT)

products short name :

[Carnitine Acetyltransferase]

other names :

[carnitine O-acetyltransferase isoform X3; Carnitine O-acetyltransferase; carnitine O-acetyltransferase; carnitine O-acetyltransferase; Carnitine acetyltransferase; CAT; CrAT]

products gene name :

[CRAT]

other gene names :

[CRAT; CRAT; CAT; CAT1; CAT1; Carnitine acetylase; CAT; CrAT]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

The antibody is a rabbit polyclonal antibody raised against CRAT. It has beenselected for its ability to recognize CRAT in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CRAT (Lys363~Leu626) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2065358

ncbi gi num :

530390532

ncbi acc num :

XP_005251765.1

ncbi gb acc num :

XM_005251708.3

uniprot acc num :

P43155

ncbi mol weight :

61,870 Da

ncbi pathways :

Beta-oxidation Of Pristanoyl-CoA Pathway (1270033); Beta-oxidation Of Very Long Chain Fatty Acids Pathway (1270034); Fatty Acid Beta Oxidation Pathway (198865); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Peroxisomal Lipid Metabolism Pathway (1270031); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Mitochondrial L-carnitine Shuttle Pathway (545348); Mitochondrial L-carnitine Shuttle Pathway (139487)

ncbi summary :

This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]

uniprot summary :

CRAT: Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. Belongs to the carnitine/choline acetyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Acetyltransferase; EC 2.3.1.7; Mitochondrial. Chromosomal Location of Human Ortholog: 9q34.11. Cellular Component: endoplasmic reticulum; mitochondrial inner membrane; mitochondrion; peroxisomal matrix; peroxisome. Molecular Function: carnitine O-acetyltransferase activity; receptor binding. Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA oxidase; transport

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

130

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

340

size6 :

1 mg

price6 :

800

more info or order :

MyBioSource product webpage