Polyclonal Antibody to Procalcitonin (PCT) | MyBioSource MBS2026689 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Procalcitonin (PCT)

catalog :

MBS2026689

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant PCT, Mouse.

image 2 :

DAB staining on IHC-P; Samples: A.Mouse Large Intestine Tissue

image 3 :

DAB staining on IHC-P; Samples: .Mouse Heart Tissue.

product information

catalog number :

MBS2026689

products type :

Antibody

products full name :

Polyclonal Antibody to Procalcitonin (PCT)

products short name :

[Procalcitonin]

other names :

[calcitonin gene-related peptide 1 isoform Calca preproprotein; Calcitonin; calcitonin gene-related peptide 1; calcitonin/calcitonin-related polypeptide, alpha]

products gene name :

[PCT]

other gene names :

[Calca; Calca; CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1; Calc]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.

concentration :

0.54 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB); Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP).

app notes :

Western blotting: 0.5-2 ug/mL;1:270-1100. Immunohistochemistry: 5-20 ug/mL;1:27-110. Immunocytochemistry: 5-20 ug/mL;1:27-110. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples: Mouse Skeletal Muscle Tissue.

other info1 :

Organism Species: Mus musculus (Mouse). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant PCT (Val26~Asn136 (Accession # P70160)) expressed in E.coli

other info2 :

Conjugate: No Conjugate. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2046068

ncbi gi num :

779176916

ncbi acc num :

NP_001292545.1

ncbi gb acc num :

NM_001305616.1

uniprot acc num :

P70160

ncbi pathways :

Calcitonin-like Ligand Receptors Pathway (1324732); Class B/2 (Secretin Family Receptors) Pathway (1324731); G Alpha (s) Signalling Events Pathway (1324736); GPCR Downstream Signaling Pathway (1324735); GPCR Ligand Binding Pathway (1324705); Myometrial Relaxation And Contraction Pathways (198333); Signal Transduction Pathway (1324550); Signaling By GPCR Pathway (1324704)

ncbi summary :

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. [provided by RefSeq, Mar 2015]

uniprot summary :

CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7 F1 7 59.99 cM. Cellular Component: axon; cell soma; cytoplasm; extracellular region; extracellular space; intracellular; neuron projection; nucleus; terminal bouton. Molecular Function: calcitonin receptor binding; hormone activity; receptor binding. Biological Process: adenylate cyclase activation; adenylate cyclase-activating G-protein coupled receptor signaling pathway; cellular calcium ion homeostasis; detection of temperature stimulus involved in sensory perception of pain; feeding behavior; inflammatory response; negative regulation of blood pressure; negative regulation of neurological process; negative regulation of ossification; negative regulation of smooth muscle contraction; neurological system process involved in regulation of systemic arterial blood pressure; neuromuscular junction development; neuropeptide signaling pathway; positive regulation of cell adhesion; positive regulation of ossification; regulation of blood pressure; regulation of heart contraction; regulation of heart rate; response to heat; response to pain; sperm capacitation; vasodilation; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

170

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

315

size6 :

1 mg

price6 :

745

more info or order :

MyBioSource product webpage