Polyclonal Antibody to Bactericidal/Permeability Increasing Protein (BPI) | MyBioSource MBS2026443 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Bactericidal/Permeability Increasing Protein (BPI)

catalog :

MBS2026443

quantity :

0.01 mg

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant BPI, Mouse.

image 2 :

DAB staining on IHC-P; Samples: Mouse Skeletal Muscle Tissue

image 3 :

DAB staining on IHC-P; Samples: Mouse Stomach Tissue.

product information

catalog number :

MBS2026443

products type :

Antibody

products full name :

Polyclonal Antibody to Bactericidal/Permeability Increasing Protein (BPI)

products short name :

[Bactericidal/Permeability Increasing Protein]

other names :

[bactericidal permeability-increasing protein isoform 1; Bactericidal permeability-increasing protein; bactericidal permeability-increasing protein; bactericidal permeablility increasing protein]

products gene name :

[BPI]

other gene names :

[Bpi; Bpi; Bpifd1; 9230105K17Rik; BPI]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Mouse

sequence length :

482

specificity :

The antibody is a rabbit polyclonal antibody raised against BPI. It has beenselected for its ability to recognize BPI in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degre C for frequent use. Aliquot and store at -20 degre C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degre C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples: Mouse Liver Tissue.

image5 heading :

Immunohistochemistry (IHC)

image5 description :

DAB staining on IHC-P; Samples: Mouse Kidney Tissue.

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid

other info2 :

Immunogen: Recombinant BPI (Asn320~Pro457) expressed in E.coli. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2052929

ncbi gi num :

29244434

ncbi acc num :

NP_808518.1

ncbi gb acc num :

NM_177850.3

uniprot acc num :

Q67E05

ncbi mol weight :

54,352 Da

ncbi pathways :

Antimicrobial Peptides Pathway (1457936); Immune System Pathway (1367472); Innate Immune System Pathway (1367502); Neutrophil Degranulation Pathway (1457939); Toll Like Receptor 4 (TLR4) Cascade Pathway (1367529); Toll-Like Receptors Cascades Pathway (1367503)

uniprot summary :

BPI: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. Protein type: Cell surface; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2 2 H1. Cellular Component: cytoplasm; extracellular region; extracellular space; membrane. Molecular Function: lipid binding; lipopolysaccharide binding. Biological Process: defense response to bacterium; defense response to Gram-negative bacterium; immune response; negative regulation of interleukin-6 production; negative regulation of interleukin-8 production; negative regulation of macrophage activation; negative regulation of tumor necrosis factor production

size1 :

0.01 mg

price1 :

110 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

175

size4 :

0.1 mg

price4 :

225

size5 :

0.2 mg

price5 :

330

size6 :

1 mg

price6 :

785

more info or order :

MyBioSource product webpage