catalog number :
MBS2026360
products full name :
Polyclonal Antibody to Cytochrome P450 11B1 (CYP11B1)
products short name :
[Cytochrome P450 11B1]
other names :
[Cytochrome P450 11B1, mitochondrial; Cytochrome P450 11B1, mitochondrial; cytochrome P450 11B1, mitochondrial; cytochrome P450, family 11, subfamily b, polypeptide 1; CYPXIB1; Cytochrome P450(11 beta)-DS; Cytochrome P450C11; Steroid 11-beta-hydroxylase (EC:1.14.15.4)]
products gene name :
[CYP11B1]
other gene names :
[Cyp11b1; Cyp11b1; Cp11ba; RATCP11BA; Cyp11b-1]
specificity :
The antibody is a Rabbit polyclonal antibody raised against CYP11B1. It has been selected for its ability to recognize CYP11B1 in immunohistochemical staining and western blotting.
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP
app notes :
Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CYP11B1 (Met1~Val498 (Accession # P15393)) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2071841
ncbi mol weight :
57,459 Da
ncbi pathways :
Aldosterone Synthesis And Secretion Pathway (1273357); Aldosterone Synthesis And Secretion Pathway (1285075); Biological Oxidations Pathway (1377788); Biosynthesis Of Aldosterone And Cortisol Pathway (198520); C21-Steroid Hormone Biosynthesis, Progesterone = Corticosterone/aldosterone Pathway (434708); C21-Steroid Hormone Biosynthesis, Progesterone = Corticosterone/aldosterone Pathway (468295); C21-Steroid Hormone Biosynthesis, Progesterone = Cortisol/cortisone Pathway (434709); C21-Steroid Hormone Biosynthesis, Progesterone = Cortisol/cortisone Pathway (468370); Cytochrome P450 - Arranged By Substrate Type Pathway (1377790); Endogenous Sterols Pathway (1377791)
ncbi summary :
catalyzes the conversion of 11-deoxycorticosterone to corticosterone [RGD, Feb 2006]
uniprot summary :
Forms corticosterone from 11-deoxycorticosterone.