Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10) | MyBioSource MBS2026297 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)

catalog :

MBS2026297

quantity :

0.01 mg

price :

135 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2026297

products type :

Antibody

products full name :

Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10)

products short name :

A Disintegrin And Metalloproteinase With Thrombospondin 10

other names :

A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 10; A disintegrin and metalloproteinase with thrombospondin motifs 10; ADAM metallopeptidase with thrombospondin type 1 motif, 10

products gene name :

ADAMTS10

other gene names :

ADAMTS10; ADAMTS10; WMS; WMS1; ADAM-TS10; ADAMTS-10; ADAM-TS 10; ADAM-TS10; ADAMTS-10

uniprot entry name :

ATS10_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

1103

specificity :

The antibody is a rabbit polyclonal antibody raised against ADAMTS10. It has beenselected for its ability to recognize ADAMTS10 in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

200ug/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid

other info2 :

Immunogen: MBS2028938-Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 10 (ADAMTS10). Manufacture date: July 2016. Expire: June 2017

ncbi gi num :

537544566

ncbi acc num :

NP_112219.3

ncbi gb acc num :

NM_030957.3

ncbi pathways :

Metabolism Of Proteins Pathway (1268677); O-glycosylation Of TSR Domain-containing Proteins Pathway (1268735); O-linked Glycosylation Pathway (1268734); Post-translational Protein Modification Pathway (1268701)

ncbi summary :

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]

uniprot summary :

ADAMTS10: Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues. Defects in ADAMTS10 are the cause of Weill-Marchesani syndrome 1 (WMS1). WMS1 is a rare connective tissue disorder characterized by short stature, brachydactyly, joint stiffness, and eye abnormalities including microspherophakia, ectopia lentis, severe myopia and glaucoma. Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.24.-; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular matrix; microfibril. Molecular Function: protein binding; zinc ion binding; metalloendopeptidase activity. Biological Process: proteolysis. Disease: Weill-marchesani Syndrome 1

size1 :

0.01 mg

price1 :

135 USD

size2 :

0.05 mg

price2 :

235

size3 :

0.1 mg

price3 :

320

more info or order :

MyBioSource product webpage