Polyclonal Antibody to Protease, Serine 2 (PRSS2) | MyBioSource MBS2026050 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Protease, Serine 2 (PRSS2)

catalog :

MBS2026050

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant PRSS2, Human.

image 2 :

Western Blot:. Sample: Porcine Pancreas Tissue.

image 3 :

DAB staining on IHC-P. Samples: Human Skin cancer Tissue. Primary Ab: 10ug/ml Rabbit Anti- Human PRSS2 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047)

product information

catalog number :

MBS2026050

products type :

Antibody

products full name :

Polyclonal Antibody to Protease, Serine 2 (PRSS2)

products short name :

[Protease]

other names :

[trypsin-2 isoform 2 preproprotein; Trypsin-2; trypsin-2; protease, serine 2; Anionic trypsinogen; Serine protease 2; Trypsin II]

products gene name :

[PRSS2]

other gene names :

[PRSS2; PRSS2; TRY2; TRY8; TRYP2; TRY2; TRYP2]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

0.56mg/ml

storage stability :

Storage:. Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

app notes :

Western blotting: 0.5-2ug/mL. Immunohistochemistry: 5-20ug/mL. Immunocytochemistry: 5-20ug/mL. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation

other info2 :

Traits: Liquid. Immunogen: Recombinant PRSS2 (Ile24~Asp241) expressed in E.coli

ncbi gi num :

4506147

ncbi acc num :

NP_002761.1

ncbi gb acc num :

NM_002770.3

uniprot acc num :

P07478

ncbi pathways :

Activation Of Matrix Metalloproteinases Pathway (1270258); Alpha-defensins Pathway (1269266); Collagen Degradation Pathway (1270259); Defensins Pathway (1269265); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); Immune System Pathway (1269170); Influenza A Pathway (217173); Influenza A Pathway (217150); Innate Immune System Pathway (1269203)

ncbi summary :

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]

uniprot summary :

trypsin 2: In the ileum, may be involved in defensin processing, including DEFA5. Belongs to the peptidase S1 family. Protein type: Calcium-binding; Cell adhesion; EC 3.4.21.4; Extracellular matrix; Protease; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7q34. Cellular Component: extracellular matrix; extracellular region; extracellular space. Molecular Function: calcium ion binding; metalloendopeptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: antimicrobial humoral response; collagen catabolic process; digestion; extracellular matrix disassembly; neutrophil degranulation; positive regulation of cell adhesion; positive regulation of cell growth; proteolysis. Disease: Pancreatitis, Hereditary

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

170

size4 :

0.1 mg

price4 :

220

size5 :

0.2 mg

price5 :

320

size6 :

1 mg

price6 :

760

more info or order :

MyBioSource product webpage