Polyclonal Antibody to Centromere Protein I (CENPI) | MyBioSource MBS2025976 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Polyclonal Antibody to Centromere Protein I (CENPI)

catalog :

MBS2025976

quantity :

0.01 mg

price :

105 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Human Raji Cells.

image 2 :

Western Blot: Sample: Recombinant CENPI, Human.

image 3 :

DAB staining on IHC-P; Samples: Human Kidney Tissue.

product information

catalog number :

MBS2025976

products type :

Antibody

products full name :

Polyclonal Antibody to Centromere Protein I (CENPI)

products short name :

[Centromere Protein I]

other names :

[centromere protein I isoform 3; Centromere protein I; centromere protein I; centromere protein I; FSH primary response protein 1; Follicle-stimulating hormone primary response protein; Interphase centromere complex protein 19; Leucine-rich primary response protein 1]

products gene name :

[CENPI]

other gene names :

[CENPI; CENPI; LRPR1; CENP-I; FSHPRH1; FSHPRH1; ICEN19; LRPR1; CENP-I]

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

specificity :

The antibody is a rabbit polyclonal antibody raised against CENPI. It has beenselected for its ability to recognize CENPI in immunohistochemical staining andwestern blotting.

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

concentration :

200ug/ml

storage stability :

Storage : Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition

tested application :

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

app notes :

Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples: Human Kidney Tissue)

image5 heading :

Immunohistochemistry (IHC)

image5 description :

DAB staining on IHC-P; Samples: Human Breast cancer Tissue)

other info1 :

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CENPI (Leu292~Gly528) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2039947

ncbi gi num :

973353086

ncbi acc num :

NP_001305452.1

ncbi gb acc num :

NM_001318523.1

uniprot acc num :

Q92674

ncbi mol weight :

59,813 Da

ncbi pathways :

Cell Cycle Pathway (1269741); Cell Cycle, Mitotic Pathway (1269763); Chromosome Maintenance Pathway (1269853); Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway (1269855); M Phase Pathway (1269810); Mitotic Anaphase Pathway (1269825); Mitotic Metaphase And Anaphase Pathway (1269823); Mitotic Prometaphase Pathway (1269820); Nucleosome Assembly Pathway (1269854); RHO GTPase Effectors Pathway (1269509)

ncbi summary :

This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016]

uniprot summary :

CENPI: involved in the response of gonadal tissues to follicle-stimulating hormone. Highly expressed in testis, ovary and spleen. Protein type: Unknown function. Chromosomal Location of Human Ortholog: Xq22.1. Cellular Component: cytosol; kinetochore; nuclear body; nucleoplasm. Molecular Function: protein binding. Biological Process: DNA replication-independent nucleosome assembly at centromere; sex differentiation; sister chromatid cohesion

size1 :

0.01 mg

price1 :

105 USD

size2 :

0.02 mg

price2 :

125

size3 :

0.05 mg

price3 :

165

size4 :

0.1 mg

price4 :

210

size5 :

0.2 mg

price5 :

305

size6 :

1 mg

price6 :

720

more info or order :

MyBioSource product webpage