catalog number :
MBS2025969
products full name :
Polyclonal Antibody to Cytochrome P450 11A1 (CYP11A1)
products short name :
[Cytochrome P450 11A1]
other names :
[cholesterol side-chain cleavage enzyme, mitochondrial; Cholesterol side-chain cleavage enzyme, mitochondrial; cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)]
products gene name :
[CYP11A1]
other gene names :
[CYP11A1; CYP11A1; CYP11A; CYPXIA1; P450(scc)]
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is les than 5% within the expiration date under appropiate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL; 1:500-2000. Immunohistochemistry: 5:20 ug/mL; 1:50-200. Immunocytochemistry: 5-20 ug/mL; 1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
other info1 :
Source: Polyclonal antibody preparation. Organism Species: Bos taurus Bovine (Cattle). Traits: Liquid. Immunogen: Recombinant CYP11A1(Val391~Gln515) expressed in E.coli.
other info2 :
Conjugated Antibody: The APC-Cy7 conjugated antibody version of this item is also available as catalog #MBS2071815
ncbi acc num :
NP_788817.1
ncbi gb acc num :
NM_176644.2
ncbi mol weight :
60,333 Da
ncbi pathways :
Aldosterone Synthesis And Secretion Pathway (1272672); Aldosterone Synthesis And Secretion Pathway (1285075); Cytochrome P450 Pathway (920888); Metabolic Pathways (132940); Ovarian Steroidogenesis Pathway (790268); Ovarian Steroidogenesis Pathway (795173); Prostaglandin Synthesis And Regulation Pathway (920923); Steroid Hormone Biosynthesis Pathway (84186); Steroid Hormone Biosynthesis Pathway (301); Steroid Hormone Biosynthesis, Cholesterol = Prognenolone = Progesterone Pathway (391030)
uniprot summary :
Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.