product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal Antibody to Utrophin (UTRN)
catalog :
MBS2025940
quantity :
0.01 mg
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
image
image 1 :
Western Blot: Sample: Recombinant UTRN, Human.
image 2 :
DAB staining on IHC-P; Samples: Human Stomach Cancer Tissue
image 3 :
DAB staining on IHC-P; Samples: Human Lung Cancer Tissue.
product information
catalog number :
MBS2025940
products type :
Antibody
products full name :
Polyclonal Antibody to Utrophin (UTRN)
products short name :
[Utrophin]
other names :
[utrophin; Utrophin; utrophin; utrophin; Dystrophin-related protein 1; DRP-1]
products gene name :
[UTRN]
other gene names :
[UTRN; UTRN; DRP; DMDL; DRP1; DMDL; DRP1; DRP-1]
clonality :
Polyclonal
host :
Rabbit
sequence length :
3433
purity :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
1 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the
expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
DAB staining on IHC-P; Samples: Human Stomach Tissue.
image5 heading :
Immunohistochemistry (IHC)
image5 description :
DAB staining on IHC-P; Samples: Human Kidney Tissue.
other info1 :
Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant UTRN (Met1~Glu252) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2077444
ncbi gi num :
110611228
ncbi acc num :
NP_009055.2
ncbi gb acc num :
NM_007124.2
uniprot acc num :
P46939
ncbi summary :
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
utrophin: May play a role in anchoring the cytoskeleton to the plasma membrane. Protein type: Dystrophin complex; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 6q24.2. Cellular Component: cell junction; contractile ring; cortical actin cytoskeleton; cytoplasm; cytoskeleton; dystrophin-associated glycoprotein complex; extracellular exosome; filopodium; filopodium membrane; growth cone; membrane; neuromuscular junction; nucleoplasm; plasma membrane; postsynaptic membrane; protein complex; sarcolemma. Molecular Function: actin binding; actin filament binding; integrin binding; protein binding; protein kinase binding; vinculin binding; zinc ion binding. Biological Process: muscle contraction; muscle organ development; neuromuscular junction development; positive regulation of cell-matrix adhesion; regulation of sodium ion transmembrane transporter activity; response to denervation involved in regulation of muscle adaptation
size1 :
0.01 mg
price1 :
110 USD
size2 :
0.02 mg
price2 :
130
size3 :
0.05 mg
price3 :
175
size4 :
0.1 mg
price4 :
225
size5 :
0.2 mg
price5 :
340
size6 :
1 mg
price6 :
800
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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