Monoclonal Antibody to Beta-2-Microglobulin (b2M) | MyBioSource MBS2025812 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Monoclonal Antibody to Beta-2-Microglobulin (b2M)

catalog :

MBS2025812

quantity :

0.01 mg

price :

100 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[A1]

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot; Sample: Rat Serum. Primary Ab: 1 ug/ml Mouse Anti-Mouse. b2M Antibody . Second Ab: 0.2 ug/mL HRP-5Linked . Caprine Anti-Mouse IgG Polyclonal Antibody . (Catalog: MBS2086035)

image 2 :

Western Blot: Sample: Recombinant b2m protein.

image 3 :

DAB staining on IHC-P Samples:Mouse Heart Tissue)

product information

catalog number :

MBS2025812

products type :

Antibody

products full name :

Monoclonal Antibody to Beta-2-Microglobulin (b2M)

products short name :

[Beta-2-Microglobulin]

other names :

[beta-2-microglobulin; Beta-2-microglobulin; beta-2-microglobulin; beta-2 microglobulin]

products gene name :

[b2M]

other gene names :

[B2m; B2m; Ly-m11; beta2m; beta2-m]

clonality :

Monoclonal

clone :

[A1]

host :

Mouse

purity :

Protein A/G Affinity Chromatography.

form :

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

concentration :

0.95mg/ml

storage stability :

Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC),Immunoprecipitation (IP)

app notes :

Western blotting: 0.5-2 ug/mL;1:470-1900. Immunohistochemistry: 5-20 ug/mL;1:47-190. Immunocytochemistry: 5-20 ug/mL;1-47-190. Optimal working dilutions must be determined by end user.

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

DAB staining on IHC-P; Samples:Mouse Liver Tissue

image5 heading :

Immunohistochemistry (IHC)

image5 description :

DAB staining on IHC-P Samples:Mouse Skeletal Muscle Tissue

other info1 :

Organism Species: Mus musculus (Mouse). Source: Monoclonal antibody preparation. Antibody isotype: IgG2a Kappa. Traits: Liquid. Immunogen: Recombinant b2M (Gln22~Met119) expressed in E.coli

ncbi gi num :

31981890

ncbi acc num :

NP_033865.2

ncbi gb acc num :

NM_009735.3

uniprot acc num :

P01887

ncbi pathways :

Adaptive Immune System Pathway (1367473); Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway (1367493); Antigen Processing And Presentation Pathway (83271); Antigen Processing And Presentation Pathway (485); Antigen Processing-Cross Presentation Pathway (1367494); Class I MHC Mediated Antigen Processing Presentation Pathway (1367491); DAP12 Interactions Pathway (1367572); DAP12 Signaling Pathway (1367573); ER-Phagosome Pathway (1367496); Endosomal/Vacuolar Pathway (1367497)

uniprot summary :

B2M: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Heterodimer of an alpha chain and a beta chain. Beta-2- microglobulin is the beta-chain of major histocompatibility complex class I molecules. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. Belongs to the beta-2-microglobulin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2 E5 2 60.55 cM. Cellular Component: cytosol; external side of plasma membrane; extracellular region; extracellular space; focal adhesion; Golgi apparatus; membrane; MHC class I protein complex; plasma membrane. Molecular Function: identical protein binding; protein binding. Biological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; cellular defense response; ferric iron import; immune response; immune system process; iron ion homeostasis; iron ion transport; positive regulation of protein binding; positive regulation of receptor-mediated endocytosis; positive regulation of T cell cytokine production; positive regulation of T cell mediated cytotoxicity; protein refolding; regulation of erythrocyte differentiation; response to molecule of bacterial origin; T cell differentiation in thymus

size1 :

0.01 mg

price1 :

100 USD

size2 :

0.02 mg

price2 :

110

size3 :

0.05 mg

price3 :

140

size4 :

0.1 mg

price4 :

175

size5 :

0.2 mg

price5 :

225

size6 :

1 mg

price6 :

505

more info or order :

MyBioSource product webpage