catalog number :
MBS2025792
products full name :
Monoclonal Antibody to Connective Tissue Growth Factor (CTGF)
products short name :
[Connective Tissue Growth Factor]
other names :
[connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; connective tissue growth factor; CCN family member 2; Connective tissue growth-related protein]
products gene name :
[CTGF]
other gene names :
[Ctgf; Ctgf; CTGRP; Ccn2]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the
expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC),Immunocytochemistry (ICC),Immunoprecipitation (IP).
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Rattus norvegicus (Rat). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CTGF (Gln25~Ala347) expressed in E.coli
other info2 :
Conjugate: No Conjugate. Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2034997
ncbi acc num :
NP_071602.1
ncbi gb acc num :
NM_022266.2
ncbi pathways :
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (935489); Gene Expression Pathway (936333); Generic Transcription Pathway (936334); Hippo Signaling Pathway (749790); Hippo Signaling Pathway (750388); Metabolism Pathway (935443); Metabolism Of Lipids And Lipoproteins Pathway (935480); PPARA Activates Gene Expression Pathway (935509); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (935508); YAP1- And WWTR1 (TAZ)-stimulated Gene Expression Pathway (936337)
ncbi summary :
growth factor that may be a mediator of TGFbeta1-driven matrix production and normal skeletal remodeling [RGD, Feb 2006]
uniprot summary :
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (). Enhances fibroblast growth factor-induced DNA synthesis ().