catalog number :
MBS2025776
products full name :
Monoclonal Antibody to Cystatin 2 (CST2)
products short name :
[Cystatin 2]
other names :
[cystatin-SA; Cystatin-SA; cystatin-SA; cystatin SA; Cystatin-2; Cystatin-S5]
products gene name :
[CST2]
other gene names :
[CST2; CST2]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-2 ug/mL;1:500-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200.
Optimal working dilutions must be determined by end user.
image1 heading :
Western Blot (WB)
other info1 :
Organism Species: Homo sapiens (Human). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CST2 (Trp21~Ala141 (Accession # P09228)) expressed in E.coli
other info2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2081181
ncbi acc num :
NP_001313.1
ncbi gb acc num :
NM_001322.2
ncbi pathways :
Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352)
ncbi summary :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008]
uniprot summary :
CST2: Thiol protease inhibitor. Belongs to the cystatin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20p11.21. Cellular Component: extracellular space. Molecular Function: cysteine-type endopeptidase inhibitor activity; protease binding; protein binding. Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste